Clinical Trials Logo

Clinical Trial Summary

The investigators will conduct a two-arm RCT to evaluate the preliminary effectiveness of a culturally-adapted video developed by the team vs. a FORCE fact sheet on enhancing genetic cancer risk assessment (GCRA; including genetic counseling and option for genetic testing) uptake and psychosocial outcomes among Latinas at increased risk for hereditary breast and ovarian cancer (HBOC).


Clinical Trial Description

The investigators will conduct a two-arm RCT to evaluate the preliminary effectiveness of a culturally-adapted video developed by the team vs. FORCE fact sheet on enhancing genetic cancer risk assessment (GCRA; including genetic counseling and option for genetic testing) uptake and psychosocial outcomes among Latinas at increased risk for hereditary breast and ovarian cancer (HBOC). All participants will receive referrals to free telephone genetic counseling in Spanish to address cost, pragmatic, and language barriers. The investigators will recruit 28 Latina women at-risk of HBOC (14 randomized at each arm) at three sites with sizable Latinx populations. The sites include community clinics/health organizations and hospitals with whom we have established collaborations [Georgetown University (DC); Virginia Commonwealth University (VA)]. Results will improve efforts to translate genomic guidelines into practice and will reduce disparities by evaluating a low cost highly disseminable culturally-targeted video while gathering data on effectiveness and implementation. Aim 1. Evaluate the impact of video vs. FORCE fact sheet on GCRA and testing uptake and psychosocial outcomes. Aim 2. Assess implementation potential and needs by evaluating feasibility, acceptability, reach, and adoption of the intervention arms (video and FORCE fact sheet) and of the HBOC screening process at the community clinics. ;


Study Design


Related Conditions & MeSH terms

  • Hereditary Breast and Ovarian Cancer Syndrome

NCT number NCT04544501
Study type Interventional
Source Georgetown University
Contact
Status Completed
Phase N/A
Start date February 24, 2020
Completion date January 31, 2022

See also
  Status Clinical Trial Phase
Completed NCT00535119 - Veliparib, Carboplatin, and Paclitaxel in Treating Patients With Advanced Solid Cancer Phase 1
Recruiting NCT03294343 - Risk-Reducing Surgeries for Hereditary Ovarian Cancer N/A
Completed NCT02956681 - Statewide Communication to Reach Diverse Low Income Women N/A
Completed NCT00305695 - Zoledronate or Observation in Maintaining Bone Mineral Density in Patients Who Are Undergoing Surgery to Remove Both Ovaries Phase 2
Active, not recruiting NCT03832985 - Pediatric Reporting of Adult-Onset Genomic Results Early Phase 1
Active, not recruiting NCT02760849 - Surgery in Preventing Ovarian Cancer in Patients With Genetic Mutations N/A
Recruiting NCT02653105 - Women at Risk of Breast Cancer and OLFM4 N/A
Completed NCT01367639 - Trial of Inquiry Based Stress Reduction (IBSR) Program for BRCA1/2 Mutation Carriers Phase 2
Completed NCT02562170 - Protexa® Versus TiLoopBra® in Immediate Breast Reconstruction- A Pilot Study Phase 4
Recruiting NCT03162276 - Trial of Inquiry Based Stress Reduction (IBSR) Program for BRCA1/2 Mutation Carriers Phase 3
Not yet recruiting NCT01445275 - Cost of Cancer Risk Management in Women at Elevated Genetic Risk for Ovarian Cancer Who Participated on GOG-0199 N/A
Recruiting NCT03015376 - Inherited Susceptible Genes Among Epithelial Ovarian Cancer
Enrolling by invitation NCT04197856 - Direct Information to At-risk Relatives N/A
Completed NCT03784859 - Tissue Expansion in Breast Reconstruction Without Drains
Completed NCT00609505 - Telemedicine vs. Face-to-Face Cancer Genetic Counseling N/A
Terminated NCT02705924 - Impact of a Psychoeducational Intervention on Expectations and Coping in Young Women Exposed to a High HBOC Risk N/A
Completed NCT01333748 - Search Allelic Imbalance of Expression of BRCA Genes in Hereditary Risk of Breast and/or Ovarian Cancer Phase 2
Completed NCT00892736 - Veliparib in Treating Patients With Malignant Solid Tumors That Do Not Respond to Previous Therapy Phase 1
Recruiting NCT05677048 - Feasibility Study: IGNITE-TX (Identifying Individuals for Genetic Testing & Treatment) Intervention N/A