Laser Assistance to Improve ICSI Outcome Clinical Trial
Official title:
Laser Assisted ICSI; Has it Role Whatsoever? Does it Affect the ICSI Outcome Positively?1
Verified date | September 2022 |
Source | Royal Fertility Center, Egypt |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
laser-assisted ICSI (LA-ICSI) was described to be a new method combining a less invasive ICSI technique with assisted hatching.This procedure is usually used for MII oocytes possessing oolemma breakage difficulties, but why not using it for even normal Oocytes?!. Especially because data indicated that in addition to an improved oocyte survival, this new approach increases the hatching rate in vitro. But since it is still debatable that such a small opening might impair the hatching process, so modified zona thinning technique was proposed for more embryo safety.
Status | Suspended |
Enrollment | 120 |
Est. completion date | January 2024 |
Est. primary completion date | December 2023 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Female |
Age group | 20 Years to 37 Years |
Eligibility | Inclusion Criteria: - Patients aged from 20 years old to 37 years old - good res-ponders - gives more than 15 oocytes - endometrial thickness more than 9 mm Exclusion Criteria: - poor res-ponders - severe oligoasthinozoospermia of male partners - testicular samples - Poor quality oocytes |
Country | Name | City | State |
---|---|---|---|
Egypt | Royal Fertility Center | Mansoura | Daqahlia |
Lead Sponsor | Collaborator |
---|---|
Royal Fertility Center, Egypt |
Egypt,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Clinical pregnancy rate | confirmed by sac observation using ultrasound | three-four weeks after embryo transfer | |
Secondary | Blastulation rate | number of blastocysts that are grown from devided embryos | 5 days later after ICSI procedure | |
Secondary | Hatching rate | number of blastocysts that hatch out of zona | 5 days later after ICSI procedure |