Effect of Ethnicity on Changes in VO2max and Cardiac Output in Response to Short-Term High Intensity Interval Training

Improved VO2max and Cardiac Output in Response to Training Clinical Trial

Official title:

Effect of Ethnicity on Changes in VO2max and Cardiac Output in Response to Short-Term High Intensity Interval Training

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04449016
• Other study ID #: 1200680-2
• Status: Completed
• Phase: N/A
• Start date: June 1, 2017
• Est. completion date: March 23, 2020

Study information

• Verified date: June 2020
• Source: California State University, San Marcos
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study was to determine if ethnicity alters training responsiveness to a low dose of high intensity interval training in inactive women.

Description:

Prior to the session, women completed a 4-minute warmup at 10 % PPO. Each subject completed 9 sessions of HIIT over a 3-week period which consisted of eight to ten 1-minute bouts of cycling at 85% PPO with 75-second recovery between bouts at 10 % PPO. This protocol is well-tolerated in inactive individuals. Continuously during each session, heart rate was monitored using telemetry. On days 1, 3, 6, and 9 of training, the physical activity enjoyment scale (PACES) was completed. VO2max and cardiac output max were assessed prior to training, as well as post.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 22
• Est. completion date: March 23, 2020
• Est. primary completion date: December 22, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 18 Years to 45 Years

Eligibility

Inclusion Criteria:

• Women

• Between the age of 18-45

• Healthy and non-obese (BMI < 30 kg/m2)

• Perform less than 150 minutes per week of exercise in the last 12 months

• 100% Caucasian or 100% Hispanic

Exclusion Criteria:

• Injured

• Obese

• Active

• Mixed ethnicity

Related Conditions & MeSH terms

• Improved VO2max and Cardiac Output in Response to Training

Intervention

Other:
• High intensity interval training
Repeated, brief, and intense exercise bouts separated by active recovery

Locations

Country	Name	City	State
United States	California State University San Marcos	San Marcos	California

Sponsors (1)

Lead Sponsor	Collaborator
California State University, San Marcos

Country where clinical trial is conducted

United States, 

References & Publications (7)

Astorino TA, Schubert MM, Palumbo E, Stirling D, McMillan DW, Cooper C, Godinez J, Martinez D, Gallant R. Magnitude and time course of changes in maximal oxygen uptake in response to distinct regimens of chronic interval training in sedentary women. Eur J Appl Physiol. 2013 Sep;113(9):2361-9. doi: 10.1007/s00421-013-2672-1. Epub 2013 Jun 11. — View Citation

Astorino TA, White AC, Dalleck LC. Supramaximal testing to confirm attainment of VO2max in sedentary men and women. Int J Sports Med. 2009 Apr;30(4):279-84. doi: 10.1055/s-0028-1104588. Epub 2009 Feb 6. — View Citation

Bowdon M, Marcovitz P, Jain SK, Boura J, Liroff KG, Franklin BA. Exercise Training in "At-Risk" Black and White Women: A Comparative Cohort Analyses. Med Sci Sports Exerc. 2018 Jul;50(7):1350-1356. doi: 10.1249/MSS.0000000000001580. — View Citation

Gill JM, Celis-Morales CA, Ghouri N. Physical activity, ethnicity and cardio-metabolic health: does one size fit all? Atherosclerosis. 2014 Feb;232(2):319-33. doi: 10.1016/j.atherosclerosis.2013.11.039. Epub 2013 Nov 23. Review. — View Citation

Johnson JL, Slentz CA, Duscha BD, Samsa GP, McCartney JS, Houmard JA, Kraus WE. Gender and racial differences in lipoprotein subclass distributions: the STRRIDE study. Atherosclerosis. 2004 Oct;176(2):371-7. — View Citation

Raleigh JP, Giles MD, Scribbans TD, Edgett BA, Sawula LJ, Bonafiglia JT, Graham RB, Gurd BJ. The impact of work-matched interval training on V?O2peak and V?O2 kinetics: diminishing returns with increasing intensity. Appl Physiol Nutr Metab. 2016 Jul;41(7):706-13. doi: 10.1139/apnm-2015-0614. Epub 2016 Feb 29. — View Citation

Skinner JS, Jaskólski A, Jaskólska A, Krasnoff J, Gagnon J, Leon AS, Rao DC, Wilmore JH, Bouchard C; HERITAGE Family Study. Age, sex, race, initial fitness, and response to training: the HERITAGE Family Study. J Appl Physiol (1985). 2001 May;90(5):1770-6. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in baseline in VO2max at 3 weeks	Each participant performed VO2max testing on an electronically-braked cycle ergometer using a ramp protocol. During exercise, subjects expired through a plastic mouthpiece and low resistance valve into tubing connected to a mixing chamber. Measures of ventilation and expired fractions of oxygen and carbon dioxide were obtained throughout exercise by a metabolic cart. Gas exchange data including VO2, VCO2, and ventilation were time-averaged every 15 seconds. The test was terminated when the subject's pedal cadence was below 50 rev/min.	3 weeks
Primary	Change in baseline in cardiac output max at 3 weeks	During the VO2max assessment, participants wore a thoracic impedance device to measure heart rate and stroke volume, calculating their cardiac output.	3 weeks