Paroxysmal Nocturnal Hemoglobinuria Clinical Trial
Official title:
A Phase III, Randomized, Open-Label, Active-Controlled, Multicenter Study Evaluating the Efficacy and Safety of Crovalimab Versus Eculizumab in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) Not Previously Treated With Complement Inhibitors.
A study designed to evaluate the non-inferiority of crovalimab compared with eculizumab in participants with PNH who have not been previously treated with complement inhibitor therapy.
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Status | Clinical Trial | Phase | |
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Recruiting |
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A Study Evaluating The Safety, Pharmacokinetics, and Efficacy Of Crovalimab Versus Eculizumab In Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Complement Inhibitors
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Phase 3 | |
Completed |
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Phase 3 | |
Recruiting |
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Active, not recruiting |
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Phase 3 | |
Recruiting |
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Phase 1 | |
Completed |
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Phase 1 | |
Completed |
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Phase 3 | |
Recruiting |
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Phase 2 | |
Completed |
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Safety and Efficacy Study of Eculizumab in Paroxysmal Nocturnal Hemoglobinuria Patients
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Phase 2 | |
Active, not recruiting |
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Phase 2 | |
Recruiting |
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Completed |
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Electronic Patient-reported Outcome Monitoring in Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria
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Active, not recruiting |
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Recruiting |
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Completed |
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A Safety and Immunogenicity Study in Long-term Treatment of Eculizumab (JSC "GENERIUM", Russian Federation)
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Phase 3 | |
Completed |
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A Study of Single-dose MY008211A in Healthy Adults
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Phase 1 | |
Recruiting |
NCT05744921 -
A Study in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) to Evaluate How Safe Long-term Treatment With Pozelimab + Cemdisiran Combination Therapy is and How Well it Works.
|
Phase 3 |