Safety and Efficacy Evaluation of ET-01 Transplantation in Subjects With Transfusion Dependent β-Thalassaemia

Transfusion Dependent Beta-Thalassaemia Clinical Trial

Official title: A Multi-center, Open Label Study to Evaluate the Safety and Efficacy of ET-01 Transplantation in Subjects With Transfusion Dependent β-Thalassemia

Status Active, not recruiting

Clinical Trial Summary

This is an open label, multi-center study to evaluate the safety and Efficacy of ET-01 Transplantation in subjects with Transfusion Dependent β-Thalassaemia.

Clinical Trial Description

After the proper subject is recruited, subject will go through steps generally as stem cell mobilization, apheresis, conditioning and ET-01 infusion to complete therapy. Two years follow-up will be carried out post-transplantation and related data will be collected. Subjects who have been treated by ET-01 will be asked to participate in a long-term follow up study. Monitoring the long-term efficacy and safety up to 15 years after ET-01 transplant. ;

Related Conditions & MeSH terms

• beta-Thalassemia
• Thalassemia
• Transfusion Dependent Beta-Thalassaemia

• NCT number: NCT04390971
• Study type: Interventional
• Source: Institute of Hematology & Blood Diseases Hospital, China
• Status: Active, not recruiting
• Phase: N/A
• Start date: February 10, 2023
• Completion date: August 15, 2025