Long Term Physical Functional Limitations in Daily Living in SARS-CoV2 Infected Patients Hospitalized in the Acute Phase Then Requiring Rehabilitation

Infection With Coronavirus SARS-CoV2 Clinical Trial

— CAPACoV19  

Official title:

Long Term Physical Functional Performance in Daily Living in SARS-CoV2 Infected Patients Hospitalized in the Acute Phase Then Requiring Rehabilitation: a Multicentric Observational Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04356378
• Other study ID #: PO20055
• Status: Completed
• Start date: June 2, 2020
• Est. completion date: January 20, 2022

Study information

• Verified date: June 2024
• Source: CHU de Reims
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Infection with coronavirus SARS-CoV2 (COVID-19 disease) is unique with its speed of propagation, structural medical reorganizations and length of stay in intensive care needed, diversity of the affected population (in particular between young persons or fragile subjects), and impact on physical and mental health generated by confinement of populations.

Fatigue is a major component of COVID-19. Global muscular weakness is related to immobility, inflammation, corticosteroids treatment, hypoxemia due to pulmonary and/or cardiac infectious attacks and undernutrition suggests major physical functional repercussions. Thus, patients affected by COVID-19 with acute hospital management require sometimes complex rehabilitation management.

Retrospective studies on physical functional capacities in patients infected with SARS CoV1 showed long term physical activity limitations.

Description:

The aim of this study is to study factors associated with physical functional limitations in daily living in patients SARS-CoV2 infected and hospitalized in the acute phase then requiring rehabilitation.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 149
• Est. completion date: January 20, 2022
• Est. primary completion date: August 20, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion criteria :

• patient infected with SARS-CoV2

• in-patient hospitalization in the acute phase because SARS-CoV2 infection

• patient requiring rehabilitation after SARS-CoV2 infection acute phase

• patient adult, aged more than 18 years old

• patient accepting to participate in the study

Exclusion criteria :

• patient with cognitive disorder (Folstein Mini-Mental State Examination less than 22 on 30 points)

Related Conditions & MeSH terms

• Coronavirus Infections
• Infection With Coronavirus SARS-CoV2

Intervention

Other:
• Data record
Data record

Locations

Country	Name	City	State
France	Damien JOLLY	Reims

Sponsors (1)

Lead Sponsor	Collaborator
CHU de Reims

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Physical functional limitations	Physical functional limitations evaluated using 'sit to stand' test. The patient, seated in a chair without armrest, his arms crossed over his shoulders, should get up and sit down without help of the upper limbs as many times as possible in one minute.	12 months