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Clinical Trial Summary

Prevention of inappropriate therapies and serious adverse cardiac and cerebrovascular events with a single chamber implantable defibrillator with DX floating dipole atrial detection


Clinical Trial Description

Prospective, randomized, open-label, multicenter, international study in a population with an accepted indication for an implantable automatic defibrillator.

The main objective is to know the different values of the rates of inappropriate therapies, of serious cardiac and cerebrovascular adverse events, and of the appropriate detections in single-chamber ICD devices, with optimized programming according to the patient's arrhythmic history, using the three discrimination methods. arrhythmias: Smart, Onset and Stability, and Morphmatch.

The device under investigation is a single chamber with a floating atrial dipole for the detection of atrial signals.

Patients who are included in the study will present an indication for an automatic cardioverter-defibrillator device according to clinical practice guidelines for an ICD and who also do not have an indication for permanent stimulation in the right atrium. For this reason, the indication of patients will be those that require an ICD without the implantation of an electrode in the atrium, that is, single-chamber ICDs or DX ICDs since both, from the therapeutic point of view, are equivalent.

The centers will follow standard clinical practice to diagnose patients ;


Study Design


Related Conditions & MeSH terms

  • Prevention of Inappropriate Therapies and MACCE. Single-chamber ICD

NCT number NCT04344704
Study type Observational [Patient Registry]
Source Trialance SCCL
Contact Xavier Molina Figueras, PharmD, PhD
Phone +34 689900009
Email xmolina@trialance.com
Status Recruiting
Phase
Start date November 2, 2018
Completion date March 2023