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Clinical Trial Summary

This trial gathers information from patients with primary central nervous system or base of skull tumors that receive proton beam therapy and see if certain imaging techniques can help detect radiation-related changes over time. This study may help providers learn more about proton beam radiotherapy and how to improve the way it is delivered.


Clinical Trial Description

PRIMARY OBJECTIVE: I. To establish linear energy transfer (LET)-based models as early predictors for white matter changes on magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) sequences in pediatric patients following proton beam therapy for primary central nervous system (CNS) and base of skull tumors. OUTLINE: Patients' medical charts are reviewed. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04296617
Study type Observational
Source Mayo Clinic
Contact
Status Completed
Phase
Start date January 21, 2019
Completion date October 23, 2023

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