Clinical and Paraclinical Characteristics of Severe Bronchiolitis in Children From 2 Months to 12 Months at the Children's Hospital 1 in Ho Chi Minh City - Vietnam

Epidemiological, Clinical, Paraclinical Characterictics of Severe Bronchiolitis Clinical Trial

Official title:

Clinical and Paraclinical Characteristics of Severe Bronchiolitis in Children From 2 Months to 12 Months at the Children's Hospital 1 in Ho Chi Minh City - Vietnam

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04174430
• Other study ID #: IRB00010193
• Status: Recruiting
• Start date: August 1, 2017
• Est. completion date: December 1, 2019

Study information

• Verified date: November 2019
• Source: Ho Chi Minh City University of Medicine and Pharmacy
• Contact: Dung Van Do, A. Professor
• Phone: +84396722467
• Email: htclan.y12e[@]ump.edu.vn
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Goal: The aim of this study is to determine the epidemiological, clinical, paraclinical characteristics and treatment of severe bronchiolitis at the Children Hospital N01 in 2001-2002.

Materials and method: in this cross-sectional study, specimens of 51 patients with severe bronchiolitis at the Children Hospital N01 from March, 1 st 2001 to February, 28th 2002 are described and analyzed.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 51
• Est. completion date: December 1, 2019
• Est. primary completion date: December 1, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 2 Months to 12 Months

Eligibility

Inclusion Criteria:

• children younger from 2-12 months present fever (usually =38.3ºC [101ºF]) ,cough, and respiratory distress (eg, increased respiratory rate, retractions, wheezing, crackles)

• preceded by a one- to three-day history of upper respiratory tract symptoms (eg, nasal congestion and/or discharge) ]

• Respiratory distress.

Exclusion Criteria:

• refusal to give informed consent

• mucus sample Barlett <=0

Related Conditions & MeSH terms

• Bronchiolitis
• Epidemiological, Clinical, Paraclinical Characterictics of Severe Bronchiolitis

Intervention

Biological:
• severe bronchiolitis
Prematurity (gestational age =36 weeks), Low birth weight, Age less than 12 weeks,Chronic pulmonary disease, particularly bronchopulmonary dysplasia (also known as chronic lung disease), Anatomic defects of the airways, Hemodynamically significant congenital heart disease, Immunodeficiency, Neurologic disease

Locations

Country	Name	City	State
Vietnam	Respiratory	Ho Chi Minh City	District 10

Sponsors (1)

Lead Sponsor	Collaborator
Ho Chi Minh City University of Medicine and Pharmacy

Country where clinical trial is conducted

Vietnam, 

References & Publications (1)

Sáez-López E, Cristóvão P, Costa I, Pechirra P, Conde P, Guiomar R; Portuguese Laboratory Network for the Diagnosis of Influenza Infection. Epidemiology and genetic variability of respiratory syncytial virus in Portugal, 2014-2018. J Clin Virol. 2019 Oct — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Number of participants with Severe bronchiolitis at the Children Hospital N01	Bronchiolitis in infants with: Preterm birth : gestational age < 37 weeks; Respiratory failure: Irritable condition; Breath rate > 50 per minute; Hypoxiemia: SpO2 < 94%; Poor feeding; Hemodynamically significant congenital heart disease (congennital heart failure, moderate to severe pulmonary hypertension or cyanotic heart disease)	2 years

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