Clinical Trials Logo
  1. Home
  2. Other
  3. NCT04162613

Can Sensorimotor Function Predict Graft Rupture After ACL Reconstruction

Anterior Cruciate Ligament Injuries Clinical Trial

Official title:
Sensorimotor Function as Predictor for Graft Rupture After Anterior Cruciate Ligament Reconstruction: A Prospective Cohort Study (STOP Graft Rupture)

Clinical Trial Summary

In this longitudinal prospective cohort study including young people with anterior cruciate ligament (ACL) reconstruction, the investigators will evaluate if poor sensorimotor function at baseline can predict 1) graft rupture 2) the risk of contra-lateral ACL injury and 3) failure to return to sport/previous activity level within 3 years following ACL reconstruction.

Clinical Trial Description

In this longitudinal prospective cohort study including young athletic men and women (aged 15-35) with ACL reconstruction (ACLR), it will be investigated if poor sensorimotor function at baseline (1 year post ACLR), such as hop performance, muscle strength and postural orientation can predict 1) graft rupture 2) the risk of contra-lateral ACL injury and 3) failure to return to sport/previous activity level within 3 years following ACLR. Statistics Separate logistic regression models will be used to elucidate the influence of each muscle sensorimotor function variable on the outcomes (graft rupture, contra-lateral injury, return to sport/activity level failure), adjusted for potential confounders. With the LSI for the single-leg hop test as main outcome, power calculations show that with a re-injury rate of 7%, an estimated odds ratio of 0.95, power=80% and alpha=5 %, at least 174 individuals are needed. Based on this calculation, 200 individuals will be included for the prospective analysis, allowing for an approximate drop-out of 10%. ;

Study Design

Related Conditions & MeSH terms

  • Anterior Cruciate Ligament Injuries
  • Rupture
Clinical Trial Details
NCT number NCT04162613
Study type Observational
Source Umeå University
Contact Anna Cronström, PhD
Phone +46707488770
Email anna.cronstrom@umu.se
Status Recruiting
Phase
Start date October 1, 2019
Completion date December 2026
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT04062578 - Effects Provided by a Physiotherapy Treatment Preventing Lower Extremity Injuries in Female Football Players N/A
Recruiting NCT05461326 - Quadriceps Tendon Versus Bone Patellar Tendon Bone Autograft ACL Reconstruction RCT N/A
Completed NCT05109871 - Reliability and Validity of Inline Dynamometry Study for Measuring Knee Extensor Torque N/A
Completed NCT05504018 - Clinical and Radiological Evaluation of ACL Reconstruction Results N/A
Recruiting NCT06185231 - Investigation of the Effects of Vibration Therapy on Pain, Functionality, and Proprioception After ACL Injury N/A
Recruiting NCT03968913 - Biologic Therapy to Prevent Osteoarthritis After ACL Injury Early Phase 1
Completed NCT04408690 - Feasibility of a RCT That Compares Immediate Versus Optional Delayed Surgical Repair After ACL Injury Phase 3
Recruiting NCT06222814 - Evaluation of the Results of Two Different Methods in Management of Antero-lateral Instability of the Knee N/A
Recruiting NCT05614297 - Agreement Between Rolimeter and Lachmeter in Patients With ACL Injury
Active, not recruiting NCT05184023 - The Effect of PEMF for Patients With Quadriceps Muscle Weakness After ACLR N/A
Completed NCT04906538 - Objective Results of Anterior Cruciate Ligament Reconstruction With and Without Internal Suture Augmentation Technique Phase 2/Phase 3
Completed NCT05014009 - The Influence of Neuromuscular Training on Whole-body Movement Strategies and Knee Mechanics During Change-of-direction Tasks in Sports Science Students N/A
Not yet recruiting NCT06083818 - Anterior Cruciate Ligament Injury Prevention Protocol in Female Football Players With Dynamic Knee Valgus N/A
Recruiting NCT05584020 - Arthroscopic Anterior Cruciate Ligament Repair Versus Reconstruction for Acute Anterior Cruciate Ligament Injury N/A
Completed NCT04580290 - Jewel ACL Post Market Clinical Follow Up Study
Recruiting NCT04888052 - Prolonged Preoperative Rehabilitation in ACL Rupture. N/A
Recruiting NCT06430775 - Exploring Prolonged AMR in ACL Reconstructed Patients
Not yet recruiting NCT05580133 - All-Inside Single-Bundle for Anterior Cruciate Ligament Reconstruction With Full Thickness of the Peroneus Longus Tendon Compared to the Six-strand-hamstring Autograft (ACL)
Not yet recruiting NCT05619393 - Comparison of Kinematic Movements Between ACL Deficiency With ACL Reconstruction and Healthy People N/A
Recruiting NCT06201442 - Post-Traumatic Knee Osteoarthritis Following Anterior Cruciate Ligament Reconstruction