Allergic Reaction Caused by Food (Disorder) Clinical Trial
Official title:
Efficacy of Oral Tolerance Induction to Raw Apple Using an Ultra Rush Protocol in 28 Rosacea Allergic Patients
The aim of the study was to describe an intensive ultra rush (UR) protocol of raw Golden apple (RGA) reintroduction in 28 in-patients, show the protocol's tolerance and the patients' follow-up at 2 months and 1 year. Patients with oral allergic syndrome (OAS) having resulted in raw fruits eviction were admitted to day hospital between June 1 2016 and October 31 2017.
The aim of this study was to describe an intensive ultra rush (UR) protocol of raw Golden
apple (RGA) reintroduction in 28 in-patients, show the protocol's tolerance and the patients'
follow-up at 2 months and 1 year. Patients with oral allergic syndrome (OAS) having resulted
in raw fruits eviction were admitted to day hospital between June 1 2016 and October 31 2017.
Methods : Patients were included during the first consultation, UR was performed with RGA in
day hospital performed in two institutions, the Charcot clinic and the polyclinic of
Beaujolais.
Starting with 1 gram (g) of food, then by regularly doubling dose from 2g to 128g, to reach a
255g cumulative dose in a 3 hour period.
During the the post hospitalization period, patients back home had to eat ½ RGA a day during
one month, then 1 RGA a day during one month, together with other rosacea fruits resumption
at the end of the 5th week if UR were performed between April 15th and July 15th. A synthesis
consultation was made at two months and a telephone interview at one year.
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