Paroxysmal Kinesigenic Choreoathetosis Clinical Trial
Official title:
Prognosis of Paroxysmal Kinesigenic Choreoathetosis in Korea: a Prospective, Observational Study
The aim of this study is to assess the prognosis of paroxysmal kinesigenic choreoathetosis (PKC) in Korean.
| Status | Recruiting |
| Enrollment | 100 |
| Est. completion date | December 31, 2026 |
| Est. primary completion date | December 31, 2026 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 18 Years and older |
| Eligibility |
Inclusion Criteria: - Male or female PKC patients who were18 years of age and older - Subjects were diagnosed as paroxysmal kinesigenic choreoathetosis (PKC) - Subjects were enrolled voluntarily and understood the contents of this trial Exclusion Criteria: - Existence of lesions on the brain - Existence of neurological deficit that suspected lesions on the brain - Existence of epileptiform discharges on electroencephalogram - Subjects with secondary PKC which was caused by other disorder or illness - Existence of illness or problems which made difficult to be enrolled to this trial judged by clinicians |
| Country | Name | City | State |
|---|---|---|---|
| Korea, Republic of | Seoul National University Hospital | Seoul |
| Lead Sponsor | Collaborator |
|---|---|
| Seoul National University Hospital |
Korea, Republic of,
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* Note: There are 11 references in all — Click here to view all references
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Changes in clinical characteristics of PKC relative to the baseline. | Improvement or worsening of the attacks relative to the baseline state assessed by a questionnaire, categorized as following; 1, full remission (absence of the attacks); 2, improvement (more than 50% decreased mean frequency of the attacks); 3, worsening (increased frequency of the attacks). | up to 10 years | |
| Primary | Changes in clinical characteristics of PKC over the last year. | Improvement or worsening of the attacks over the last year assessed by a questionnaire, categorized as following; 1, full remission (absence of the attacks); 2, improvement (more than 50% decreased mean frequency of the attacks); 3, worsening (increased frequency of the attacks). | up to 10 years | |
| Primary | Changes in medication history of PKC over the last year. | Continuation or discontinuation of the medication for relief of the attacks assessed by a questionnaire, categorized as following; 1, continuation of medication; 2, discontinuation of medication. | up to 10 years |