BMAC Nerve Allograft Study

Peripheral Nerve Injury Upper Limb Clinical Trial

Official title: Clinical Evaluation of Decellularized Nerve Allograft With Autologous Bone Marrow Aspirate Concentrate (BMAC) to Improve Peripheral Nerve Repair and Functional Outcomes

Status Active, not recruiting

Clinical Trial Summary

This study is a prospective, multi-center, proof of principle, phase I human safety study evaluating the sequential treatments of the Avance Nerve Graft, a commercially available decellularized processed peripheral nerve allograft, with autologous Bone Marrow Aspirate Concentrate (BMAC), a source of stem cells, for the repair of peripheral nerve injuries up to 7 cm in length. The purpose of this study is to establish a knowledge product, evaluating the safety profile of the Avance Nerve Graft, followed by the application of BMAC to support further investment into the promising area of using stem cells in conjunction with scaffolds.

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Peripheral Nerve Injuries
• Peripheral Nerve Injury Upper Limb

• NCT number: NCT03964129
• Study type: Interventional
• Source: Brooke Army Medical Center
• Status: Active, not recruiting
• Phase: N/A
• Start date: August 22, 2017
• Completion date: June 1, 2021