Clinical Trials Logo

Clinical Trial Summary

This is an open-label, phase 2 study of KN026 in subjects with HER2 expressing gastric/gastroesophageal junction cancer to evaluate efficacy and safety. The subjects will receive KN026 10 mg/kg QW or 20 mg/kg Q2W or 30mg/kg Q3W until progressive disease, unacceptable toxicity or death.


Clinical Trial Description

The study consists of two arms as HER2 overexpression arm and HER2 expression arm and both arms will receive KN026 treatment. ;


Study Design


Related Conditions & MeSH terms

  • Gastric/Gastroesophageal Junction Cancer

NCT number NCT03925974
Study type Interventional
Source Jiangsu Alphamab Biopharmaceuticals Co., Ltd
Contact
Status Completed
Phase Phase 2
Start date June 17, 2019
Completion date May 31, 2022

See also
  Status Clinical Trial Phase
Active, not recruiting NCT03847168 - KN026 in Patients With HER2 Expressing Breast Cancer and Gastric Cancer Phase 1
Completed NCT03941873 - A Study to Investigate Sitravatinib as Monotherapy and in Combination With Tislelizumab in Participants With Unresectable Locally Advanced or Metastatic Hepatocellular Carcinoma (HCC) or Gastric/Gastroesophageal Junction Cancer (GC/GEJC) Phase 1/Phase 2