Macular Edema Caused by Leber's Miliary Aneurysms Clinical Trial
Official title:
Treatment of Macular Edema Caused by Leber's Miliary Aneurysms Using Intravitreal Aflibercept and Peripheral Laser Photocoagulation
| NCT number | NCT03908723 |
| Other study ID # | 21526 |
| Secondary ID | |
| Status | Recruiting |
| Phase | N/A |
| First received | |
| Last updated | |
| Start date | March 29, 2019 |
| Est. completion date | May 29, 2021 |
This study evaluates the effectiveness of intravitreal Aflibercept (IVA) injection therapy, combined with peripheral laser photocoagulation, in the treatment of macular edema caused by Leber's miliary aneurysm. We believe that our study makes a significant contribution to the literature because to our knowledge, it is the first to report cases, in which IVA injection therapy was used to treat this condition.
| Status | Recruiting |
| Enrollment | 6 |
| Est. completion date | May 29, 2021 |
| Est. primary completion date | March 29, 2021 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 14 Years and older |
| Eligibility |
Inclusion Criteria: - FA revealed many aneurysms with leakage in the temporal mid-peripheral retina and near the macula. Optical coherence tomography (OCT) showed moderate to marked cystoid macular edema and subretinal fluid. There were no abnormal findings in the cornea, anterior chamber, or lens. No particular lesions were found in the opposite eye of each subject. Based on these findings, the patients were diagnosed with Leber's miliary aneurysm. Exclusion Criteria: |
| Country | Name | City | State |
|---|---|---|---|
| Egypt | Alexandria university | Alexandria |
| Lead Sponsor | Collaborator |
|---|---|
| Alexandria University |
Egypt,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Visual acuity improvement | 6 months after 3 consequative injections |