Comparison Between Local and Imported Skin Prick Testing Result of Rat and Mouse Allergen Extracts

Allergic Rhinitis Due to Animal Hair and Dander Clinical Trial

Official title:

Comparison Between Local and Imported Skin Prick Testing Result of Rat and Mouse Allergen Extracts in Respiratory Allergy Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03645161
• Other study ID #: 789/2560 (EC 2)
• Status: Completed
• Phase: N/A
• Start date: May 30, 2018
• Est. completion date: July 30, 2019

Study information

• Verified date: August 2019
• Source: Mahidol University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

In respiratory allergy patients, skin prick test results of local rat and mouse allergen extracts are not significant different from imported ones

Description:

Many researches proposed that rodent deteriorate symptoms in patients with respiratory allergy who sensitized. The test that can identify rodent sensitization will be very useful. The investigators found lots of problems from imported mouse and rat allergen extract, eg. expensive cost and hard to find importing agency in Thailand. Making own local allergen extract will be the good solution for the country. This study aim to compare the results of locally rat and mouse allergen to imported ones.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 230
• Est. completion date: July 30, 2019
• Est. primary completion date: May 30, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 3 Years to 60 Years

Eligibility

Inclusion Criteria:

• Patients age 3 to 60 years old who diagnosed with asthma or allergic rhinitis

• Patient must not take these following medication at least 7 days before doing the skin prick test: antihistamine, oral corticosteroid (more than 20 mg/day of prednisolone), topical steroid that was apply on skin test area.

Exclusion Criteria:

• Pateints who have other chronic underlying disease e.g. obesity, heart disease and liver disease

• Patient with allergic asthma who is still uncontrollable.

• Patient with active severe atopic dermatitis

• Patient who are pregnant or in lactating period

• Patient or parent deny to join in the study

Related Conditions & MeSH terms

• Allergic Rhinitis Due to Animal Hair and Dander
• Rhinitis
• Rhinitis, Allergic

Intervention

Diagnostic Test:
• rat and mouse skin test
Comparison between local and imported skin prick testing result of rat and mouse allergen extracts in respiratory allergy patients

Locations

Country	Name	City	State
Thailand	Siriraj Hospital. Mahidol University	Bangkok

Sponsors (1)

Lead Sponsor	Collaborator
Mahidol University

Country where clinical trial is conducted

Thailand, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Comparison between local and imported skin prick testing result of rat and mouse allergen extracts in respiratory allergy patients	Compare the results of locally rat and mouse allergen to imported ones.	1 year