Rhegmatogenous Retinal Detachment Clinical Trial
Official title:
Patching Retinal Breaks With Healaflow in 27G Vitrectomy for the Treatment of Rhegmatogenous Retinal Detachment
To report the surgical results of primary rhegmatogenous retinal detachment (RRD) repaired by 27G pars plana vitrectomy (PPV) combined with Healaflow patch and air tamponade, and do not need prone position postoperation.
To improve the success rates of pars plana vitrectomy(PPV) which is the most common surgical
procedure for the repair of primary rhegmatogenous retinal detachment (RRD) and to avoid
silicon oil tamponade and face-down position, all eyes enrolled into this clinical trail
undergo 27G PPV combined with Healaflow patch and air tamponade which do not need face-down
position in the postoperative period. Healaflow® (Anteis S.A., Plan Les Ouates, Switzerland)
consists of over 97% water, sodium hyaluronic acid (22.5 mg/ml) of nonanimal origin
cross-linked with BDDE (1.4-Butanediol diglycidyl ether), and phosphate- and NaCl-salts to
maintain a physiological pH (7.0) and osmolarity (305 mOsm/kg).
At the time of study enrollment, physical examinations, best-corrected visual acuity (BCVA),
intraocular pressure(IOP) will be measured and fundoscopy, OCT, B-ultrasound will be
performed.
The patients are going to be followed up for at least 3 months, the main outcome measures are
postoperative primary and final anatomic outcome, BCVA and complications.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT04403750 -
Combined Laser-surgical Technology of RRD Treatment
|
N/A | |
| Not yet recruiting |
NCT04520789 -
Early Prevention Strategies of Severe Proliferative Vitreoretinopathy Base on Precision Diagnosis of Single Cell Sequencingvitreoretinopathy
|
N/A | |
| Recruiting |
NCT04571788 -
Treating Rhegmatogenous Retinal Detachment by Foldable Capsular Buckle
|
||
| Completed |
NCT02834559 -
Prophylactic Intravitreal 5-Fluorouracil and Heparin to Prevent PVR in High-risk Patients With Retinal Detachment.
|
Phase 3 | |
| Recruiting |
NCT01845571 -
Retinal Detachment - Demographic and Clinical Survey
|
||
| Completed |
NCT04891991 -
Intravitreal Infliximab for Proliferative Vitreoretinopathy
|
Phase 2 | |
| Recruiting |
NCT02871531 -
Pneumatic Retinopexy Versus Vitrectomy for Retinal Detachment in Patients With Extended Criteria
|
N/A | |
| Completed |
NCT00757536 -
Primary Vitrectomy With Endolaser or Encircling Band for Rhegmatogenous Retinal Detachment
|
N/A | |
| Active, not recruiting |
NCT00370201 -
Efficacy of Oral Colchicine in Prevention of Proliferative Vitreoretinopathy in Rhegmatogenous Retinal Detachment
|
Phase 3 | |
| Completed |
NCT00345007 -
Macular Function After Scleral Buckle
|
N/A | |
| Recruiting |
NCT05331664 -
Dropless Pars Plana Vitrectomy Study
|
Phase 4 | |
| Completed |
NCT02841306 -
Ursodeoxycholic Acid for Rhegmatogenous Retinal Detachment
|
Phase 1 | |
| Not yet recruiting |
NCT02185469 -
Corneal Endothelial Cell Loss After Pneumatic Retinopexy for the Repair of Primary Rhegmatogenous Retinal Detachment
|
N/A | |
| Not yet recruiting |
NCT01647373 -
Axial Length Change in Eyes Treated by Silicone Sponge Scleral Buckling
|
N/A | |
| Completed |
NCT01068379 -
Clinical Trial of Cryotherapy Versus Postoperative Laser Photocoagulation
|
Phase 3 | |
| Not yet recruiting |
NCT06468397 -
Acute Retinal Detachment Repair With the iSeelr^TM Retinal Detachment Repair System
|
N/A | |
| Not yet recruiting |
NCT06425419 -
The Safety and Efficacy of Intravitreal Topotecan for the Treatment of Proliferative Vitreoretinopathy
|
Phase 1 | |
| Recruiting |
NCT06056596 -
Lamivudine and Plasma Markers of Inflammation in Retinal Detachment
|
Early Phase 1 | |
| Completed |
NCT01343134 -
Anatomical and Functional Macular Changes in Retinal Detachment
|
N/A | |
| Recruiting |
NCT05588037 -
Combined Vitrectomy and Femtosecond Laser-assisted Cataract Surgery
|
N/A |