Oppositional Defiant Disorder With Familial Setting Clinical Trial
— TOPiOfficial title:
Observational Study on Intrafamilial Oppositional Defiant Disorder (IODD) in Children and Adolescents
Verified date | February 2018 |
Source | University Hospital, Montpellier |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Oppositional Defiant Disorder (ODD) is defined in the Diagnostic and Statistical Manual of
Mental Disorders, Fifth Edition (DSM 5) as: "A pattern of angry/irritable mood,
argumentative/defiant behavior, or vindictiveness lasting at least 6 months exhibited during
interaction with at least one individual who is not a sibling." "The disturbance in behavior
is associated with distress in the individual or others in his or her immediate social
context (e.g., family, peer group, work colleagues), or it impacts negatively on social,
educational, occupational, or other important areas of functioning." Children with "classic"
oppositional defiant disorder, except for mild forms, show symptoms in several settings (at
home, at school, with peers).
In this study, the investigators will consider the specifics of children presenting
"intrafamilial" oppositional defiant disorder (IODD). These children's symptoms are confined
to only one setting: the home. Therefore, the aim of this study will be to characterize
children with intrafamilial oppositional defiant disorder. The investigators want to
understand the differences between IODD and classical forms of ODD in terms of psychiatric
comorbidities, medical histories and cognitive abilities. They also investigate what
clinicians currently do to help these families.
Status | Completed |
Enrollment | 75 |
Est. completion date | December 31, 2017 |
Est. primary completion date | December 31, 2017 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 5 Years to 16 Years |
Eligibility |
Inclusion criteria: - Child diagnosed with ODD with KSADS_PL - Child who was evaluated during a day evaluation at one of our unit cares: UDS (Unité de Diagnostic et de Soins) or UPP (Unité de Prévention Pédosychiatrique) - Child included in the "REACT" study - 16 years old or under Exclusion criteria: - Child who has not been diagnosed with ODD - Missing data in the parent report SDQ or teacher report SDQ preventing the SDQ total score calculation |
Country | Name | City | State |
---|---|---|---|
France | Uhmontpellier | Montpellier |
Lead Sponsor | Collaborator |
---|---|
University Hospital, Montpellier |
France,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Other | Assesment of Verbal Comprehension Index | The Verbal Comprehension Index (VCI) is a score derived from the administration of selected subtests from the fourth and the fifth Wechsler Intelligence Scale for Children (WISC). It is designed to provide a measure of verbal acquired knowledge and verbal reasoning. (See Encyclopedia of Clinical Neuropsychology) | 1 day | |
Other | Perceptual Reasoning Index | The WISC IV provides four index scores: Verbal Comprehension Index, Processing speed Index,Working Memory Index, Perceptual Reasoning Index. The WISC V provides 5 index scores: Verbal Comprehension Index, Visual Spatial Index, Fluid Reasoning Index, Working Memory Index, and Processing Speed Index. |
1 day | |
Other | Working Memory Index | The WISC IV provides four index scores: Verbal Comprehension Index, Processing speed Index,Working Memory Index, Perceptual Reasoning Index. The WISC V provides 5 index scores: Verbal Comprehension Index, Visual Spatial Index, Fluid Reasoning Index, Working Memory Index, and Processing Speed Index. |
1 day | |
Other | Processing Speed Index | The WISC IV provides four index scores: Verbal Comprehension Index, Processing speed Index,Working Memory Index, Perceptual Reasoning Index. The WISC V provides 5 index scores: Verbal Comprehension Index, Visual Spatial Index, Fluid Reasoning Index, Working Memory Index, and Processing Speed Index. |
1 day | |
Other | Visuo Spatial Index | The WISC IV provides four index scores: Verbal Comprehension Index, Processing speed Index,Working Memory Index, Perceptual Reasoning Index. The WISC V provides 5 index scores: Verbal Comprehension Index, Visual Spatial Index, Fluid Reasoning Index, Working Memory Index, and Processing Speed Index. |
1 day | |
Other | Fluid Reasoning Index (FRI) | It is a score derived from the administration of selected subtests from the fifth Wechsler Intelligence Scale for Children (WISC). It allows to detect underlying conceptual relationships among visual objects |
1 day | |
Other | Prevalence of somatic diseases in patient medical history | Past somatic diseases were mentioned in the patient medical record. We classified them into: Serious illness (chronic illness, hospitalisation needed, treatment taken for several months) Less serious illness. |
1 day | |
Other | Socio-economic status of the family assessed by parents' occupation | Parents' occupation were classified into 6 categories derived from the INSEE classification (Institut national de la statistique et des études économiques) | 1 day | |
Other | Family situation | Family situation: number of siblings, birth rank among siblings, single parents, divorced parents Description:This information is in the medical reports, it is mentioned in the questionnaire that is always filled by parents before the first consultation of their child. | 1 day | |
Primary | Measure of the prevalence of the anxiety disorder diagnosis | The psychometric test used to characterize the specific primary outcome measure is the Kiddie-SADS-PL Schedule For Affective Disorders and Schizophrenia for School Age Children Present and Lifetime Version. The K-SADS-PL is a semi-structured interview aimed at early diagnosis of affective disorders such as anxiety disorder, depression, bipolar disorder. It generates reliable and valid child psychiatric diagnoses (1). It is specifically designed for school children aged 6 to 18. In this study, the K-SADS-PL test is performed by psychiatry residents or by psychologists. The interview is performed during the evaluation day (hospital day care) or during the pre-study visit for patients participating in the " react " protocole. |
1 day | |
Secondary | Measure of Intellectual qQuotient | The Wechsler Intelligence Scale for Children (WISC) is an individually administered intelligence test for children aged 6 to 16. The test generates a Full Scale IQ (formerly known as an intelligence quotient or IQ score) that represents a child's general intellectual ability. In our study, both WISC IV and WISC V have been used. The Fifth Edition is the most current version, and has therefore been used for the most recent tests. The WISC IV provides four index scores: Verbal Comprehension Index, Processing speed Index,Working Memory Index, Perceptual Reasoning Index (see below). The WISC V provides 5 index scores: Verbal Comprehension Index, Visual Spatial Index, Fluid Reasoning Index, Working Memory Index, and Processing Speed Index (see below). For the measure of the intellectual quotient and for the measure of all the index scores, the average is 80-120. Bellow average values represents poorer outcome. |
1 day |