Hepatitis C and B VIRUS Screening, Awareness and Behavior Assessment and Evaluation for All Inhabitants Above Twelve Years of Al Othmaneya Village Clinical Trial
Official title:
Use of Public Health Approaches for HCV Elimination in an Egyptian Model Village
| Verified date | January 2018 |
| Source | National Research Center, Egypt |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Interventional |
Elimination of hepatitis C virus (HCV) is the process of stopping sustained transmission of viral hepatitis, reducing its incidence to zero and providing access to safe, affordable and effective treatment and care for everyone. Consequently, HCV will not be a leading cause of mortality (1). The World Health Organization (WHO) called for comprehensive programs that enhance access to affordable treatment in developing countries as HCV was considered a global public health priority since 2010 and set criteria of elimination(2). A disease is eliminated if its controlling efforts are sufficient to prevent an epidemic from occurring in a given geographical area and measures must be continued to prevent re-establishment of transmission (3) According to the Centers for Disease Control and Prevention (CDC), HCV now surpasses HIV as the nation's deadliest blood-borne disease. In addition, the majority of infected persons are not aware of their infection as they are not clinically ill and there is no vaccine for Hepatitis C. It is well known that the best way to prevent Hepatitis C is by avoiding behaviors that can spread the disease. (4) This study is a way forward for the elimination of hepatitis C from Egypt through applying different public health approaches for motivating people and changing villagers' risky behaviors aiming at increasing the number of people adopting healthy practices for decreasing the incidence rate of hepatitis in El Othmaneya village. The proposed activities along one year were applied for 3575 inhabitants aged more than 12 years who were get tested for Hepatitis C Virus (HCV) antibodies. The initiative activities were provided by community-led coalition and supported technically by the Egyptian Liver Research Institute and Hospital (ELRIAH).
| Status | Completed |
| Enrollment | 3575 |
| Est. completion date | October 21, 2017 |
| Est. primary completion date | May 13, 2017 |
| Accepts healthy volunteers | Accepts Healthy Volunteers |
| Gender | All |
| Age group | 12 Years and older |
| Eligibility |
Inclusion Criteria: All village inhabitants starting from 12 years old Exclusion Criteria: inhabitants less than 12 years old |
| Country | Name | City | State |
|---|---|---|---|
| n/a | |||
| Lead Sponsor | Collaborator |
|---|---|
| National Research Center, Egypt | Egyptian Liver Hospital |
4) Center for Disease Control (CDC). Division of Viral Hepatitis (DVH) Strategic Plan, 2016-2020: Bringing Together Science and Public-Health Practices for the Elimination of Viral Hepatitis. (2016). http://www.cdc.gov/hepatitis/pdfs/dvh-strategicplan2016-2020-draft.
Barrett S. Eradication versus control: the economics of global infectious disease policies. Bull World Health Organ. 2004 Sep;82(9):683-8. — View Citation
Heymann DL. Control, elimination, eradication and re-emergence of infectious diseases: getting the message right. Bull World Health Organ. 2006 Feb;84(2):82. Epub 2006 Feb 23. — View Citation
WORLD HEPATITIS SUMMIT HARNESSES GLOBAL MOMENTUM TO ELIMINATE VIRAL HEPATITIS. Cent Eur J Public Health. 2015 Sep;23(3):272. — View Citation
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | percent change of awareness using pre and post intervention questionnaire for participants who became aware of the problem | Using previously used syringes Sharing shaving equipment, nail cutters or through needle stick injury Defect in infection control process during sessions for teeth treatment sharing tooth brush with other family members It is better for HCV patients to get vaccinated with Hepatitis B vaccines Using new syringes/sharp instruments which are not used before could reduce the risk of becoming infected with HCV Awareness by the recommended behaviors can limit the complication and propagation of HCV infection |
two years | |
| Primary | Percent change using pre and post intervention questionnaire for participants who became concerned about the problem,acquired knowledge and internalized the knowledge | Perception: HCV is a serious disease HCC is a complication of HCV Cirrhosis is a complication of HCV Early diagnosis could make a change in patients' health Fatigue from least effort is symptom of HCV |
two years | |
| Primary | Percent change using pre and post intervention questionnaire for participants who became motivated and had positive attitude to do something about the problem | The Attitude: Asking the barber: to change the shaving tools in front of them to use their own shaving machine Checking for sterilized tools at dentist clinic Telling the dentist if they have/ had HCV |
two years | |
| Primary | Percent change of behavior using pre and post intervention questionnaire for participants who tried out /rejected or adopted the recommended behavior | The tried out / rejected or adopted : Not sharing: nail cutters and scissors between family members loofah and sponge for personal cleaning the use of scarves' pins by the veiled females in the same family other's shaving tools others tooth brushes |
two tears |