Spermatogenesis and Semen Disorders Clinical Trial
Official title:
In Vitro Effects of Procyanidine on Semen Parameters and DNA Fragmentation Index: a Prospective, Double-blind Trial
Proanthocyanidins are a class of polyphenols found in a variety of plants that have
antioxidant activity in vitro, which is stronger than vitamin C or vitamin E.
Several studies have been performed evaluating the administration of antioxidant therapy in
the form of oral antioxidant supplementation or in vitro addition of antioxidant to culture
media during assisted reproductive techniques (ART).
However, the impact of in vitro addition of proanthocyanidins to semen has not been studied
yet. The research question evaluated in the current study was whether semen samples of
infertile men supplemented or not with procyanidine immediately after their production,
differ in semen parameters, sperm DFI.
n/a
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