Clinical Trials Logo

Clinical Trial Summary

Background: Few studies have investigated the difference of bacterial contamination between conventional reused ventilator systems and disposable closed ventilator-suction systems. The aim of this study was to investigate the bacterial contamination rates of the reused and disposable ventilation systems, and the association between system disconnection and bacterial contamination of ventilator systems.

Methods: The enrolled patients used a conventional reused ventilator system and a disposable closed ventilator-suction system, respectively, for a week; specimens were then collected from the ventilators' internal system to evaluate human and environmental bacterial contamination. The sputum specimens from patients were also analyzed in this study.

Results: The detection rate of bacteria in the conventional reused ventilator system was substantially higher than that in the disposable system. The inspiratory and expiratory limbs of disposable closed ventilator-suction system had higher bacterial concentrations than the conventional reused ventilator system. The bacterial concentration in the heated humidifier (HH) of the reused system was significantly higher than that in the disposable system. Positive associations existed among the bacterial concentrations at different locations in the reused and disposable ventilator systems, respectively. The predominant bacteria identified in the reused and disposable ventilator systems included Acinetobacter spp., Bacillus cereus, Elizabethkingia spp., Pseudomonas spp., and Stenotrophomonas (Xan) maltophilia.

Conclusion: Both the reused and disposable ventilation systems had high bacterial contamination rates after one week of use. Disconnection of the ventilator systems should be avoided during system operation for decreasing the risks of environmental pollution and human exposure, especially for the disposable system.


Clinical Trial Description

The intubated and mechanically ventilated patients were enrolled from the Intensive Care Unit of Chang Gung Memorial Hospital, Taiwan. The experimental study group was assigned to a disposable ventilator system combined with an auto-filled heated humidifier (HH), a closed suction catheter, and a closed aerosol therapy procedure with a valved T-adaptor. According to clinical commonly used system, the control study group was assigned to use with conventional reused ventilator system, combined with a manually filled HH, an open suction catheter, and a conventional aerosol therapy procedure. Every patient was use above both ventilator systems. ;


Study Design


Related Conditions & MeSH terms

  • Contaminated Medical or Biological Substances
  • Environmental-Pollution-Related Condition

NCT number NCT03359148
Study type Observational [Patient Registry]
Source Chang Gung University
Contact
Status Completed
Phase N/A
Start date April 2, 2015
Completion date July 31, 2016

See also
  Status Clinical Trial Phase
Completed NCT05976126 - Characterization of a Population Living in Highly Contaminated Settlement in Campania Region
Completed NCT04124562 - Nitrous Oxide Frequency of Use and Causes in Hospital in Turkey
Completed NCT05686031 - An Evaluation of Operating Room Staff's Awareness of Environmental Sustainability and Medical Waste Management
Completed NCT06127862 - Microplastica Pollution Awareness Level of Students N/A
Recruiting NCT05729581 - Effectiveness of Educational Intervention on Sustainable Breastfeeding: The GREEN MOTHER Project N/A