Adult Patients Undergoing Elective Surgery With General Anesthesia and LMA Insertion Clinical Trial
Official title:
Comparison Between Lidocaine Inhalation and Intravenous Dexamethasone to Reduce Pain After Laryngeal Mask Insertion
Verified date | August 2017 |
Source | Indonesia University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This study aimed to compare the efficacy between lidocaine inhalation vs intravenous dexamethasone to reduce pain after laryngeal mask insertion
Status | Completed |
Enrollment | 196 |
Est. completion date | May 31, 2017 |
Est. primary completion date | January 31, 2017 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 20 Years to 59 Years |
Eligibility |
Inclusion Criteria: - patients aged 20-59 years old, with American Society of Anesthesiologists (ASA) physical status of I-II who were planned to undergo any elective surgery at operating room in general anesthesia and needed LMA insertion - Mallampati class I or II - subjects had been explained about the study, and agreed to enroll and have signed the informed consent form - Subjects without history of throat pain Exclusion Criteria: - Subjects with cardiovascular disease, history of analgetic and steroid before surgery, surgical site of neck, oral cavity, pharynx, and larynx - Subjects with upper respiratory tract infection - Subjects with history of drug allergy used in the trial and possibility of difficult airway - Pregnant, obese, active smoking, uncontrolled diabetic and hypertension subjects - Subjects with history of peptic ulcer disease. Dropout Criteria: - Subjects whose LMA insertion attempts more than once - Subjects with surgery duration > 150 minutes - Subjects who needed mechanical ventilation after surgery, subjects who vomitted - Subjects whose LMA converted to endotracheal tube during surgery - Subjects who received additional opioid during surgery |
Country | Name | City | State |
---|---|---|---|
Indonesia | Cipto Mangunkusumo Central National Hospital | Central Jakarta | DKI Jakarta |
Lead Sponsor | Collaborator |
---|---|
Indonesia University |
Indonesia,
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Seet E, Yousaf F, Gupta S, Subramanyam R, Wong DT, Chung F. Use of manometry for laryngeal mask airway reduces postoperative pharyngolaryngeal adverse events: a prospective, randomized trial. Anesthesiology. 2010 Mar;112(3):652-7. doi: 10.1097/ALN.0b013e3181cf4346. — View Citation
Sun L, Guo R, Sun L. Dexamethasone for preventing postoperative sore throat: a meta-analysis of randomized controlled trials. Ir J Med Sci. 2014 Dec;183(4):593-600. doi: 10.1007/s11845-013-1057-0. Epub 2013 Dec 20. Review. — View Citation
Uztüre N, Menda F, Bilgen S, Keskin Ö, Temur S, Köner Ö. The Effect of Flurbiprofen on Postoperative Sore Throat and Hoarseness After LMA-ProSeal Insertion: A Randomised, Clinical Trial. Turk J Anaesthesiol Reanim. 2014 Jun;42(3):123-7. doi: 10.5152/TJAR.2014.35693. Epub 2014 Mar 11. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Numerical rating scale | Numerical rating scale for throat pain | Day 1 |