Blood Contamination of Root Canal During Endodontic Therapy Clinical Trial
Official title:
A New Approach for Controlling Hemostasis During Canal Treatment: a Pilot Study
Blood contamination, such as apical microleakage, of root canal during preparation can be a major problem in endodontics. The purpose of this investigation was to evaluate the hemostatic properties of sulfonic/sulfuric acid solution used during root canal therapy in teeth with irreversible pulpitis.
A new device (HYBENX®) has been developed with the purpose of destroying dental biofilm. The
material contains a concentrated aqueous mixture of hydroxybenzenesulfonic acid (37%) and
hydroxymethoxybenzene acids (23%), sulfuric acid (28%), and water (12%).
The investigators planned a clinical and microbiological study using the decontaminant device
in order to destroy the dental biofilm of root canals in cases of irreversible pulpitis. The
ability of the decontaminant device to immediately stop bleeding during canal instrumentation
was found out accidentally during the procedures of this still unpublished trial.
Due to this fact, the investigators were interested in evaluating the coagulation property of
the material. Therefore, the aim of this prospective study is to describe a new approach to
obtain hemostasis during root canal therapy using a sulfonic/sulfuric acid solution.
A total of 15 teeth with irreversible and acute pulpitis were included in the study. After
manual and mechanical instrumentation of the root canal, a sterile paper point was introduced
in the canal, and a first score was given based on the blood quantity.
The solution was used to irrigate the bleeding root canal; then a second sterile paper point
was introduced, and the same score was assessed. The null hypothesis was that there is no
difference in root canal bleeding before and after the use of the solution (⎧=0)
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03336853 -
A New Approach for Controlling Hemostasis During Canal Treatment
|
N/A |