Patients in Minimally Conscious State Clinical Trial
In this study，researchers will use personalized objects to assess patients' level of consciousness in chronic patients in minimally conscious state (MCS).
The Coma Recovery Scale-Revised (CRS-R) is an important tool for the assessment of behaviors
in DOC.Clinical practice has shown that self-referential stimuli, such as the patient's own
name and face, are more effective to elicit the patient's response than that of
non-self-referential stimuli.
The item "Functional Object Use" was assessed by using personalized objects (e.g.,
cigarette, paper) and non-personalized objects, which presented in a random order.The rest
assessments were performed following the standard protocol of CRS-R. The differences between
functional use of the two types of objects was analyzed by Chi-square test.
Researchers expected to see some of the patients in MCS are re-diagnosed as EMCS with the
using of personalized objects.
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Allocation: Randomized, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Diagnostic