Post-transplantation Lymphoproliferative Disorders Clinical Trial
Official title:
Array-CGH in Plasma Cell Post-transplantation Lymphoproliferative Disorders
Plasma-cell post-transplantation lymphoproliferative disorders (PC-PTLD) are rare monomorphic PTLD divided into plasma cell myeloma (PCM) and plasmacytoma-like lesion (PLL) PTLD. To date, there is no exhaustive published cytogenetic data on PC-PTLD. The investigators report array-based comparative genomic hybridization (aCGH) of 10 cases of PCM and PLL-PTLD.
| Status | Completed |
| Enrollment | 10 |
| Est. completion date | June 2016 |
| Est. primary completion date | January 2012 |
| Accepts healthy volunteers | No |
| Gender | Both |
| Age group | N/A and older |
| Eligibility |
Inclusion Criteria: - WHO classification 2008 as monomorphic PCM (plasma cell myeloma) or PLL (plasmacytoma like lesion) / PTLD (post transplantation lymphoproliferative disorders). Exclusion Criteria: - Other than PCM or PLL PTLD at diagnosis |
Time Perspective: Retrospective
| Country | Name | City | State |
|---|---|---|---|
| France | Centre hospitalier Lyon sud | Pierre Bénite | Rhône Alpes |
| Lead Sponsor | Collaborator |
|---|---|
| Hospices Civils de Lyon |
France,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Genome wide array-based comparative genomic hybridization (aCGH) | At diagnosis of PTLD, Day 0. | No | |
| Secondary | Overall survival according to aCGH complexity | Overall survival (OS) was calculated from date of diagnosis to date of death from any cause, up to 130 months. | No |