Ventilator-Associated Lung Injury Clinical Trial
Official title:
Ventilator-Associated Events: Prevalence, Outcome and Preventability
The aim of this study is to determine the prevalence of ventilator-associated events (VAE). To analyze the patients profile, morbidity and mortality compared to patients who did not develope VAE. The preventability of VAE will be assessed by comparing the percentage of adherence to the bundle of preventive measures among patients who developed and did not develope VAE.
This is a retrospective analysis of prospectively collected data, approved by the Research
Ethics Committee of Hospital Sao Domingos. The need for informed consent was waived.
Included were all patients admitted to a surgical (13 beds) and medical (32 beds) of a
tertiary hospital over a 3-year period (February 2013 to January 2016), aged above 18 years
and submitted to mechanical ventilation for at least 4 days.
At admission and daily the following data were collected: head of bed elevation, daily
interruption of sedation, gastric ulcer prevention, Thromboembolism prophylaxis, aspiration
of subglottic secretions, oral care with chlorhexidine gluconate and monitoring of
endotracheal tube cuff pressure.
Identification of VAE, Ventilator-associated condition (VAC), Infectious condition
associated to mechanical ventilation (IVAC) and ventilator-associated pneumonia possible and
probable followed definition criteria of the National Healthcare Safety Network / Center for
Disease Control and Prevention.
The percentage of adherence to the bundle of preventive measures of VAE prevention was
registered.
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Observational Model: Cohort, Time Perspective: Retrospective
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