Relationship of Obesity With GERD Among Nigerians

Gastro-esophageal Reflux Disease With Ulceration. Clinical Trial

Official title:

Relationship Between Body Mass Index, Waist Circumference, Waist Hip Ratio and Erosive Gastroesophageal Reflux Disease in a Tertiary Centre in Nigeria: a Case Control Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02888808
• Other study ID #: ERC/2009/03/07
• Status: Completed
• Phase: N/A
• First received: August 12, 2016
• Last updated: August 30, 2016
• Start date: March 2013
• Est. completion date: December 2015

Study information

• Verified date: August 2016
• Source: Obafemi Awolowo University Teaching Hospital
• Contact: n/a
• Is FDA regulated: No
• Health authority: Nigeria: Federal Ministry of Health
• Study type: Observational

Clinical Trial Summary

Obesity is a strong risk factor for GERD. This study assessed the role of obesity among patients having erosive GERD and controls.

Description:

A case control study of patients with erosive GERD. Patients with erosive GERD who had upper gastro-intestinal endoscopy were graded using the Los Angeles classification. Patients and controls had measurements of body mass index (BMI), WC (waist circumference), Waist hip ratio (WHR), and hip circumference (HC). Bio-data was collected from both groups and data were analysed using descriptive and inferential statistics. A p value of equal to or less than 0.05 was considered significant.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 160
• Est. completion date: December 2015
• Est. primary completion date: December 2015
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Patients with dyspepsia

Exclusion Criteria:

• Patients that refused consent.

• Patients with gastric cancer

• Patients with gastric outlet obstruction

• Pregnant women

• Active gastrointestinal bleeding

• Cigarette smokers

• Patients on Naso-gastric tube.

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

• Gastro-esophageal Reflux Disease With Ulceration.
• Gastroesophageal Reflux
• Ulcer

Intervention

Other:
• Gastroscopy
Upper gastrointestinal endoscopy procedure

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Obafemi Awolowo University Teaching Hospital

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Obesity associated with GERD	Measurement of anthropometric indices	Immediate.	Yes
Secondary	Body mass index is associated with GERD	Measurement of body mass index (kilogram per meter squared)	Immediate	Yes
Secondary	Waist circumference is associated with GERD	Measurement of waist circumference (centimeter)	Immediate	Yes
Secondary	Waist hip ratio is associated with GERD	Measurement of waist hip ratio	Immediate	Yes