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Clinical Trial Summary

Acute central serous chorioretinopathy (CSC) is a common disorder in middle-aged patients, characterized by serous retinal detachment in the macular region. We evaluated half-dose verteporfin photodynamic therapy (hd-PDT) versus 689 nm laser treatment in chronic CSC.

Twenty-two eyes of 22 patients with symptomatic chronic CSC were randomized in a 1:1 ratio to receive hd-PDT (group 1) or 689-LT delivering 95 J/cm2 by application of an intensity of 805 mW/cm2 over 118 seconds. Best-corrected visual acuity (BCVA) and spectral-domain optical coherence tomography findings were compared between groups.


Clinical Trial Description

n/a


Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT02799992
Study type Interventional
Source Università degli Studi di Brescia
Contact Andrea Russo, MD, PhD
Phone +390303995308
Email dott.andrea.russo@gmail.com
Status Not yet recruiting
Phase N/A
Start date June 2016
Completion date September 2016

See also
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Completed NCT00489840 - Treatment of Chronic Central Serous Chorioretinopathy With Open-Label Anecortave Acetate Phase 1/Phase 2
Completed NCT00211393 - A Pilot Study of the Treatment of Central Serous Chorioretinopathy With Ketoconazole Phase 2
Completed NCT02462499 - Eplerenone Treatment for Chronic Central Serous Chorioretinopathy in Hungarian Population Phase 4
Completed NCT01325181 - Ranibizumab Versus Low-fluence Photodynamic Therapy in the Treatment of Chronic Central Serous Chorioretinopathy Phase 1/Phase 2
Completed NCT00211445 - Photodynamic Therapy Using Verteporfin for Treatment of Chronic Central Serous Chorioretinopathy (CSC) Phase 2
Active, not recruiting NCT03079141 - Photodynamic Therapy Versus Eplerenone: Treatment Trial for Chronic Central Serous Chorioretinopathy Phase 4
Recruiting NCT05633576 - Steroid Eye Drops in Chronic Central Serous Chorioretinopathy Phase 3
Completed NCT01797861 - Prospective Randomized Controlled Treatment Trial for Chronic Central Serous Chorioretinopathy Phase 4
Completed NCT04224831 - Treatment of Chronic Central Serous Chorioretinopathy Via Electromagnetic Stimulation and Platelet- Rich Plasma N/A