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Clinical Trial Assessing the HERV-W Env Antagonist GNbAC1 for Efficacy in MS — CHANGE-MS  

Multiple Sclerosis, Relapsing-Remitting Clinical Trial

Official title:
An International, Double-blind, Randomised, Placebo-controlled Phase IIb Trial to Assess the Efficacy, Safety, and Pharmacokinetics of GNbAC1 in Patients With Relapsing Remitting Multiple Sclerosis

Clinical Trial Summary

The humanised IgG4 monoclonal antibody GNbAC1 targets the envelope protein (Env) of the human endogenous multiple sclerosis-associated retrovirus (HERV-W MSRV), which may play a critical role in multiple sclerosis (MS). This study evaluates the effect on MRI lesions parameters, the safety and pharmacokinetics of GNbAC1 in patients with relapsing remitting multiple sclerosis.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02782858
Study type Interventional
Source GeNeuro SA
Contact
Status Completed
Phase Phase 2
Start date April 2016
Completion date December 2017
View Details
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