Prucalopride Plus Polyethylene Glycol in Bowel Preparation for Colonoscopyp Clinical Trial
Prucalopride based bowel cleansing regimen might be helpful to improve bowel cleansing quality before colonoscopy.
Colonoscopy is the standard approach for evaluating the colon currently. Thorough bowel
cleansing is critical for adequate visualization of colonic mucosa during colonoscopy.
Inadequate bowel cleansing results in adverse consequences for the examination, including
lower adenoma detection rates, longer procedural time, lower cecal intubation rates, shorter
intervals between examinations and an estimated 12-22% increase in overall colonoscopy
cost.Unfortunately, despite advances in bowel preparation methods, up to one-third of all
colonoscopies are reported to have an inadequate bowel preparation.
Prucalopride can accelerate colonic transit and has been demonstrated to be efficient in
constipation.
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Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment