Detection of Preeclampsia Complications Clinical Trial
Official title:
Correlation Between Complications of Pre-eclampsia and Detection of Novel Biochemical Markers
In view of both endothelial injury in pre-eclampsia, high blood pressure and kidney
impairment characteristics, a recent study demonstrated that the serum levels of NGAL
increased at the end of the second trimester in women who subsequently developed
pre-eclampsia compared to the control group.
This correlates well with the endothelial damage that occurs during pre-eclampsia and thus
NGAL can be considered as a promising marker in predicting both early and late onset
pre-eclampsia. It may be required to combine one or more biomarker with NGAL to increase the
precision, and sensitivity for detection of risk and reliability of using biomarkers for
pre-eclampsia.
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