Clinical trial NCT02616484 - References

Pyruvate Dehydrogenase Complex Deficiency — Trial of Dichloroacetate in Pyruvate Dehydrogenase Complex Deficiency:

Citation(s)

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•   Robinson BH
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•   Shroads AL, Coats BS, McDonough CW, Langaee T, Stacpoole PW
  Haplotype variations in glutathione transferase zeta 1 influence the kinetics and dynamics of chronic dichloroacetate in children. J Clin Pharmacol. 2015 Jan;55(1):50-5. doi: 10.1002/jcph.371. Epub 2014 Aug 6.
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  Human polymorphisms in the glutathione transferase zeta 1/maleylacetoacetate isomerase gene influence the toxicokinetics of dichloroacetate. J Clin Pharmacol. 2012 Jun;52(6):837-49. doi: 10.1177/0091270011405664. Epub 2011 Jun 3.
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Phase 3 Trial of Dichloroacetate in Pyruvate Dehydrogenase Complex Deficiency:

Details for clinical trial NCT02616484