The Biological Effect of ESWT and the Role of Proinflammatory Cytokines and Cannabinoid Receptor in Shoulder Stiffness

Stiffness of Shoulder, Not Elsewhere Classified Clinical Trial

Official title: The Biological Effect of Extracorporeal Shockwave Technology (ESWT) and the Role of Proinflammatory Cytokines and Cannabinoid Receptor in Shoulder Stiffness

Status Recruiting

Clinical Trial Summary

Investigators recent data showed anti-inflammatory effect of Effect of Extracorporeal Shockwave Technology (ESWT). Little studies focused on the effect and pathomechanism of ESWT on shoulder stiffness.

Clinical Trial Description

1. First year:Investigators intend to further delineate the inflammatory mechanism, such as IL-1β, CB1, HSP in the incidence of shoulder stiffness.

2. Second year: Investigators intend to conduct a prospective randomized double-blind study for the clinical effect of ESWT on patients with shoulder stiffness.

3. Third year: Investigators wish to test the biologic effect of ESWT on patients with shoulder stiffness and to elucidate the molecular mechanism for this effect through a randomized comparative study. ;

Related Conditions & MeSH terms

• Stiffness of Shoulder, Not Elsewhere Classified

• NCT number: NCT02450864
• Study type: Interventional
• Source: Chang Gung Memorial Hospital
• Contact: Jih-Yang Jih-Yang, MD
• Phone: 886-7-731-7123
• Email: kojy@cgmh.org.tw
• Status: Recruiting
• Phase: N/A
• Start date: January 1, 2013
• Completion date: July 31, 2019