Acute Kidney Injury After Adult Cardiac Surgery Clinical Trial
Official title:
The Association Between Hydroxyethyl Starch 130/0.4 and Acute Kidney Injury After Cardiopulmonary Bypass: a Single-center Retrospective Study
| Verified date | October 2015 |
| Source | University Hospital of Liege |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | Belgium: Ethics Committee |
| Study type | Observational |
This study retrospectively assess the effect or using balanced hydroxyethyl sctarch (HES) 130/0.4 or a balanced crystalloid solution as a pump prime and for intraoperative fluid therapy on the risk of early acute postoperative kidney injury in adult cardiac surgery patients.
| Status | Completed |
| Enrollment | 697 |
| Est. completion date | July 2015 |
| Est. primary completion date | July 2015 |
| Accepts healthy volunteers | No |
| Gender | Both |
| Age group | 18 Years and older |
| Eligibility |
Inclusion Criteria: - Age = 18 yo - Having on pump cardiac surgery at CHU of Liège between April 2013 and June 2014 Exclusion Criteria: - Off pump surgery - Use of Blood or Albumin in the cardiopulmonary bypass priming solution - Preoperative dialysis |
Observational Model: Cohort, Time Perspective: Retrospective
| Country | Name | City | State |
|---|---|---|---|
| n/a | |||
| Lead Sponsor | Collaborator |
|---|---|
| University Hospital of Liege |
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | AKIN SCr | Stage of acute kidney injury using the Acute Kidney Injury Network Classification omitting the diuresis criteria. | Forty eight hours | No |
| Secondary | AKIN SCr+UO | Stage of acute kidney injury using the Acute Kidney Injury Network Classification including the diuresis criteria. | Forty eight hours | No |
| Secondary | Postoperative dialysis | Requirement of postoperative renal replacement therapy | 30 days | No |
| Secondary | Respiratory complication | Need for reintubation, non-invasive ventilation or prolonged intensive care unit stay as a consequence of atelectasis, pulmonary edema or pneumonia. | 30 days | No |
| Secondary | ICU stay | Length of stay at the intensive care unit | 30 days | No |
| Secondary | Hospital stay | Length of stay at the hospital | 30 days | No |
| Secondary | 30-day mortality | Death in hospital or within 30 days of surgery | 30 days | No |