Explore the Association Between Neuropsychological Functions and ADHD Diagnosis and Comorbid Using Longitudinal Study in Preschool Children

Attention Deficit/Hyperactivity Disorder Clinical Trial

Official title: Explore the Association Between Neuropsychological Functions and ADHD Diagnosis and Comorbid Using Longitudinal Study in Preschool Children

Status Recruiting

Clinical Trial Summary

The current study using the longitudinal study in preschool children to exam three study issues: 1) using the neuropsychological functions (ie. Behavioral inhibition, delay aversion, the variability of reaction time) among the preschool children predict the ADHD diagnosis and behavior symptoms in 1.5 years later. 2) using the behavior inhibition, delay aversion and the variability of reaction time (using the parameter among Gaussian distribution and ex-Gaussian distribution) explore the association between attention and motor inhibition problems. 3) explore the transaction effect between the neuropsychological functions and family function and parenting to predict ADHD comorbidity with oppositional defiant disorder.4) explore the association between the internalizing/ externalizing problems of ADHD and temperament. The current study has opportunity to describe and to answer the complicated problems for heterogeneous neuropsychological deficits in ADHD, and to elucidate the core issues for ADHD have comorbid with ODD. The most important contribution is to offer the empirical evidence to make a clean suggestion in ADHD diagnosis and intervention in preschool age.

Clinical Trial Description

The current study would follow the same participants for 1.5 years, time 1 is around 4-5 years old, and time 2 is around 6-7 years old.

Participants:

• 100 typical developmental control

• 120 ADHD high risk preschool children at time 1

The diagnosis at time 2 to have three groups in this study:

• ADHD persistent

• ADHD remission

• typical developmental control

The measurements were included

• the different neuropsychological test (ie. behavioral inhibition, delay aversion, and vigilance task)

• the ADHD behavioral rating scales and diagnosis interview

• the scaling for family function and parenting

• intellectual assessment

This study could offer the suggestion for the further intervention in ADHD. ;

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

• Attention Deficit Disorder with Hyperactivity
• Attention Deficit/Hyperactivity Disorder

• NCT number: NCT02433145
• Study type: Observational
• Source: National Taiwan University Hospital
• Contact: Susan Shur-Fen Gau, MD, PhD
• Phone: 02-23123456
• Email: gaushufe@ntu.edu.tw
• Status: Recruiting
• Phase: N/A
• Start date: October 2014
• Completion date: August 2017