Clinical Trials Logo

Clinical Trial Summary

The hypothesis is that CES stimulation will dose dependently increase parasympathetic tone. Healthy subjects will have three 20 minute sessions of CES stimulation, at three different intensities of stimulation, with each session occurring on a separate day. Effect on parasympathetic tone will determined by measuring high frequency heart rate variability before, during and after the stimulation. The Fisher Wallace Stimulator (FW100) which delivers a low dose alternating current a varying frequencies will be used for the stimulation.


Clinical Trial Description

Healthy subjects will have three 20 minute sessions of bitemporal CES stimulation, at three different intensities of stimulation (sham, 1 milli Amp, 2 milli Amp), with each session occurring on a separate day. The Fisher Wallace Stimulator (FW100) which delivers a low dose alternating current a varying pulsed frequencies (5 Hertz, 500 Hertz, and 25000 Hertzz) will be used for the stimulation. ECG will be recorded continuously for 15 minutes before stimulation, during 20 minute stimulation and for 15 minutes following stimulation. Effect on parasympathetic tone will determined by measuring high frequency heart rate variability before, during and after the stimulation. Effect of CES of heart rate and low frequency heart rate variability will also be examined. Subject side effects will also be assessed. ;


Study Design


Related Conditions & MeSH terms

  • Autonomic Nervous System Imbalance

NCT number NCT02163967
Study type Interventional
Source Weill Medical College of Cornell University
Contact
Status Completed
Phase Phase 4
Start date January 11, 2013
Completion date March 15, 2013

See also
  Status Clinical Trial Phase
Completed NCT03616275 - Enhancing the Vagal Tone in Prediabetes Individuals N/A
Completed NCT01736137 - Evaluation of the Six Minute Walk Test and Other Instruments in Heart Failure N/A
Completed NCT03362944 - Active and Passive Music Therapy Interventions N/A
Completed NCT04636970 - Unobtrusive Technologies for Monitoring of Autonomic Nervous System Function in Elderly Frail Patients N/A
Completed NCT03888456 - Effects of OMT on ANS: a Thermography Study N/A
Withdrawn NCT03332043 - HIRREM for Pre-Hypertension N/A
Not yet recruiting NCT03144791 - Lighting and Human Response in Motor Time, Autonomic Nervous System, and Emotion N/A
Completed NCT03244891 - Autonomic Challenges From Mild Hypovolemia and Mechanical Ventilation N/A
Recruiting NCT03955159 - Effects of Probiotic Supplementation in Hypertensive Women on Menopause N/A
Not yet recruiting NCT06217133 - Heart Rate Variability of Premature Newborn N/A
Recruiting NCT03302923 - Brisk Walking Study in Nursing Home Residents N/A
Recruiting NCT04125953 - Stochastic Modulated Vibrations on Autonomic Nervous System of Breast Cancer Patients During Radiotherapy N/A
Completed NCT03613961 - Effects of Propofol Induction Anaesthesia on the Heart Rate Variability
Completed NCT05906940 - Vagus Nerve Stimulation for Autonomic Nervous System Activity N/A
Completed NCT03704025 - Home-based Exercise Training in Cardiac Patients N/A
Completed NCT03441009 - Metabolism and the Activity of the Autonomic Nervous System in Patients With Paroxystic Sympathetic Hyperactivity, PSH
Completed NCT03479697 - HIRREM for Stage 1 Primary Hypertension N/A
Completed NCT05500716 - The Effect of Vagus Nerve Stimulation on Temporomandibular Joint Dysfunction N/A
Recruiting NCT04428619 - Percutaneous Electrical Nerve Field Stimulation for Adults With Irritable Bowel Syndrome N/A
Recruiting NCT04732572 - Brain Tissue Integrity and Autonomic Function Alterations in Childhood OSA and ADHD, and After Adenotonsillectomy. N/A