FSHD - Facioscapulohumeral Muscular Dystrophy Clinical Trial
Official title:
High Intensity Interval Training in Patients With Facioscapulohumeral Muscular Dystrophy
The investigators aim to investigate the effect of high-intensity training in patients with facioscapulohumeral muscular dystrophy. Can patients benefit from this type of exercise without muscle damage.
Clinical trials have in recent years demonstrated that aerobic exercise, are both effective
and safe in patients with facioscapulohumeral muscular dystrophy. Previous studies have
tested exercise at moderate intensity. No studies have so far investigated whether
high-intensity-training (HIIT) exercise can increase fitness, or the training will cause
muscle damage. However, we know that patients with facioscapulohumeral muscular dystrophy do
not get increased muscle damage after a single exercise at high intensity.
Investigators aim to investigate whether patients with facioscapulohumeral muscular disease
may increase their fitness and improve their functioning in everyday life without muscle
injury in a time-saving high intensity training.
To investigate whether HIIT is safe and effective, three groups of participants are
included. Two training groups, one group of patients and another with healthy matched
subjects. The training is done on an ergometer-bike three times a week for 8 weeks. One
weekly training will be supervised. The training consists of an interval training program
(10-20-30). The third group is a none-training control group of patients. This group will
undergo the same tests as the two training groups.
To investigate wether participants would continue HIIT training after 8 weeks of supervised
training, the two training groups, one group of patients and one group of healthy matched
subjects, are tested after additional 8 weeks of home based optional training.
To investigate wether patients with muscular dystrophy facioscapulohumeral will perform
unsupervised HIIT training and whether it will be as effective as the supervised training,
the control group of patients who did not train the first 8 weeks, is instructed to do home
based HIIT for 8 weeks.
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Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Supportive Care
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02159612 -
1 Year MRI Followup in Facioscapulohumeral Muscular Dystrophy
|
N/A |