Assessment of the Psychological, Cognitive and Social Resources of Applicants for Huntington's Disease and Presymptomatic Genetic Testing

Presymptomatic Huntington Disease Clinical Trial

— PREHUNT  

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02134561
• Other study ID #: 2013-A00088-37
• Status: Completed
• Phase: N/A
• Start date: September 2013
• Est. completion date: August 2018

Study information

• Verified date: February 2013
• Source: University Hospital, Angers
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to assess the psychological, cognitive and social resources of applicants for Huntington's Disease and Presymptomatic Testing.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 24
• Est. completion date: August 2018
• Est. primary completion date: August 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Applicants for Huntington's Disease and Presymptomatic Testing
• Aged 18 years and above
• Huntington disease family member
• Subject gave its written consent

Exclusion Criteria:

• No national health insurance affiliation
• Being under guardianship
• Meeting brain MRI exclusion criteria (pacemakers, aneurysm clips, artificial heart valves, ear implants, metal fragments or foreign objects in the eyes, skin, or body, Renal failure, hypersensitivity of Gadolinium) or refusing MRI.
• Patient with movement disorder

Related Conditions & MeSH terms

• Huntington Disease
• Presymptomatic Huntington Disease

Intervention

Behavioral:
• psychological interview

Radiation:
• MRI
This MRI is a specific intervention assign to the subjects of the study, that's why it is an interventionnal study

Other:
• cognitive tests

• neurological tests

Locations

Country	Name	City	State
France	University Hospital of Angers	Angers	Pays De La Loire

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Angers

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change from baseline total score of the psychological Unified Huntington's Disease Rating Scale at 2 years		3 months before diagnostic (baseline) ; 2 years after diagnostic,