Obstructive Chronic Bronchitis With Acute Exacerbation Clinical Trial
Official title:
Effectiveness of Respiratory Therapy in Acute Exacerbations of Chronic Obstructive Pulmonary Disease
The purpose of this study is to determine effectiveness, feasibility and safety/tolerance of Respiratory Therapy in hospitalized patients with acute exacerbations of chronic obstructive pulmonary disease.
Acute exacerbation of chronic obstructive pulmonary disease (AE-COPD) is defined as an event
in the natural course of the disease characterized by a change in the patient's usual
symptoms (dyspnea, cough and/or sputum) that may not be explained by the daily variations
and requires a change in regular medication.
Because AE-COPD result in impairment of both pulmonary and respiratory muscle functions, as
well as an increasing impact on costs, priority should be given to interventions to slow the
progression of the disease, prevention of exacerbations and reduce the risk of comorbidity.
Chest physiotherapy is often used in hospitalized patients with AE-COPD with the aim of
favoring the removal of secretions and thus to improve the ventilation perfusion (V/Q), and
therefore the function lung. The limited scientific evidence has determined that their use
is controversial and not routinely recommended in clinical practice guidelines. Current
clinical guidelines in the treatment of COPD are unable to rule on the application of
respiratory therapy during exacerbations, since there is little scientific evidence of its
benefits in the short and long term.
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Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02481908 -
STI Combined to Valsalva Maneuver for the Diagnosis of Left Ventricular Dysfunction in COPD Exacerbations
|