Locally Advanced Malignant Neoplasm Clinical Trial
Official title:
Healthy Bones Study: An Intervention to Improve Healthy Bone Behaviours in Prostate Cancer Patients on Androgen Deprivation Therapy (ADT)
Prostate cancer patients receiving hormone treatment (androgen deprivation therapy, or ADT)
are at increased risk of developing bone loss and osteoporosis as side effects. To prevent
this, guidelines recommend participation in healthy bone behaviours including weight-bearing
exercise and adequate calcium/vitamin D intake. However, prior studies have shown that
patients are not regularly screened or counselled regarding healthy bone behaviours while
receiving ADT. Maintaining bone health in prostate cancer patients is important because men
on ADT are at increased risk of fractures. In this study, the investigators will examine
whether an intervention designed to improve healthy bone behaviours among prostate cancer
patients on ADT can be implemented. The intervention consists of a written "healthy bones
prescription", brief verbal counseling, and printed educational materials for participants.
Investigators hope to obtain an initial estimate of whether the intervention works. They
also hope to show that this simple intervention can be implemented in a real, working cancer
clinic.
The investigators hypothesize that an intervention to improve bone health in prostate cancer
patients receiving ADT (healthy bones prescription, verbal counseling, and printed
educational materials) is effective, implementable, and accepted by clinicians and patients.
The study has a before-and-after design, to allow comparison of the intervention before its
implementation and after its implementation. This design permits a reliable assessment of
baseline characteristics prior to implementation of intervention and over time, particularly
in situations where randomization is not feasible (e.g. due to contamination of treating
physicians). The point at which the intervention will start to be delivered for new study
participants is when 150 patients are accrued to the Before arm.
1. Before/control arm (Before arm) Usual care by Princess Margaret Cancer Centre (PM)
oncologist.
2. After/intervention arm (After arm) Provision of a healthy bones prescription, verbal
counselling, and written educational materials regarding healthy bone behaviours by PM
oncologist or delegate (e.g. clinical fellow), in addition to usual care by oncologist.
The intervention may be delivered again at a subsequent follow-up at the request of the
patient and/or at the discretion of the oncologist.
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Active, not recruiting |
NCT03671226 -
Preference of Room Setting and Waiting Time in Patients With Advanced, Locally Advanced, or Metastatic Cancer and Their Caregivers Who Are Seen in the Outpatient Supportive/Palliative Care Center
|
N/A | |
Completed |
NCT01876927 -
Pre-Operative Or Peri-Operative Dox Regimen In Patients With Locally Advanced Resectable Gastric Cancer
|
Phase 2 | |
Terminated |
NCT03295942 -
A Study of OMP-336B11 in Subjects With Locally Advanced or Metastatic Tumors
|
Phase 1 | |
Completed |
NCT03238027 -
A Phase 1 Study to Investigate Axatilimab Alone or in Combination With Durvalumab in Patients With Solid Tumors
|
Phase 1 | |
Recruiting |
NCT04260802 -
A Study to Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers
|
Phase 1/Phase 2 | |
Completed |
NCT02823652 -
Pre-Test Genetic Education and Remote Genetic Counseling in Communicating Tumor Profiling Results to Patients With Advanced Cancer
|
N/A | |
Completed |
NCT02227082 -
Olaparib and Radiotherapy in Inoperable Breast Cancer
|
Phase 1 | |
Recruiting |
NCT01871363 -
Phase II Study of Preoperative IMRT Combined With Capecitabine and Bevacizumab in Locally Advanced Rectal Cancer
|
Phase 2 | |
Completed |
NCT01847001 -
Study of Propranolol in Newly Diagnosed Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy
|
Phase 2 | |
Terminated |
NCT03170115 -
Induction Chemotherapy Plus Chemoradiotherapy With or Without Aspirin in High Risk Rectal Cancer
|
Phase 2 | |
Recruiting |
NCT04749108 -
Study Evaluating the Tailored Management of Locally-advanced Rectal Carcinoma
|
Phase 2/Phase 3 | |
Terminated |
NCT01836432 -
Immunotherapy Study in Borderline Resectable or Locally Advanced Unresectable Pancreatic Cancer
|
Phase 3 | |
Recruiting |
NCT01675999 -
Trial of Neoadjuvant Chemotherapy in Locally Advanced Colon Cancer
|
Phase 2 | |
Completed |
NCT01333709 -
Multicenter Phase 2 Trial: a Tailored Strategy for Locally Advanced Rectal Carcinoma
|
Phase 2 | |
Completed |
NCT01325558 -
A Study of ALT-836 in Combination With Gemcitabine for Locally Advanced or Metastatic Solid Tumors
|
Phase 1 | |
Withdrawn |
NCT03849742 -
Ride to Care - Quality of Life With Transportation for RT
|
N/A | |
Active, not recruiting |
NCT03856060 -
Videos and Questionnaires in Assessing Patient Perception of Physician's Compassion, Communication Skills, and Professionalism During Clinic Visits
|
N/A | |
Completed |
NCT04186884 -
Caregiver Burden, Quality of Life, and Symptom Distress at Different Palliative Cancer Care Settings
|
||
Recruiting |
NCT04112836 -
Pancreatic Cancer Malnutrition and Pancreatic Exocrine Insufficiency in the Course of Chemotherapy in Unresectable Pancreatic Cancer
|
||
Not yet recruiting |
NCT03051152 -
D1 Versus D2 Lymphadenectomy in High Risk Elderly With Gastric Adenocarcinoma
|
N/A |