Affected and Unaffected Knee in Adoloescent Clinical Trial
— Knee- MRI 2012Official title:
Dynamic Kine-mri in Patellofemoral Instability in Adolescents- an Aid in the Diagnosis
Purpose: The impact of kinematic-MRI (KINE-MRI) in the patellofemoral instability and anterior knee pain of the adolescents is rarely reported.Interest was to evaluate the patellofemoral joint biomechanics with KINE-MRI in adolescents with affected and unaffected knees in a case-control study.Methods: KINE-MRI was performed in 29 adolescents (affected knee group, AKG, n=29 and n=26 unaffected knee group, UAKG, n=26) aged 11-16 years with unilateral patellofemoral instability. For the control group invvestigators enrolled ten healthy age- and sex-matched volunteers (healthy knee group, HKG, n=19 ).The study parameters, Bisect Offset (BSO), Lateral Patellar Displacement (LPD), Patellar Tilt Angle (PTA), Sulcus Angle and Insall-Salvati ratio at 0, 10, 20 and 30 degrees of flexion-extension, were measured for the AKG patients (n=29), and UAKG patients (n=26) and the HKG subjects (n=19). Results: In a comparison between the AKG patients and the HKG subjects there was a significant difference in the BSO-ratio, LPD-test and PTA-test. In these parameters the difference between the AKG patients and the HKG subjects progressively increased towards the full extension of the knee. In the AKG and UAKG patients BSO-ratio at 0 degree ranged between 0.5 and 1.2 in both groups, whereas the BSO-ratio in the HKG subjects ranged between 0.33 and 0.75 (P < .001). At the zero degree the LPD-test ranged between 0 and 10 mm in the AKG patients and between 0 and 35 mm in the UAKG patients, whereas the lateral displacement-test ranged between 0 and 5 mm in the HKG subjects (P = .003). Patellar tilt angle-test ranged between -30 and 20 degrees in the AKG patients and between -30 and 24 degrees in the UAKG patients and in the HKG subjects the PTA-test ranged between 10 and 24 degrees (P < .001).Conclusion: The KINE-MRI could be a feasible method for the evaluation of patellar tracking in adolescents.
| Status | Completed |
| Enrollment | 50 |
| Est. completion date | January 2013 |
| Est. primary completion date | January 2013 |
| Accepts healthy volunteers | Accepts Healthy Volunteers |
| Gender | Both |
| Age group | 10 Years to 16 Years |
| Eligibility |
Inclusion Criteria: - The inclusion criteria for the 29 patients were as follows: objective patellar instability with or without objective or episodic patellar dislocation, anterior knee pain for more than one year with positive apprehension tests, J-tracking of the patella, lateral tilt and displacement proven clinically. Exclusion Criteria: - did not enroll any patients with the knee trauma, the previous surgery and the osteochondritic lesions. |
Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Diagnostic
| Country | Name | City | State |
|---|---|---|---|
| Finland | Kuopio University Hospital | Kuopio | Northern Savo |
| Lead Sponsor | Collaborator |
|---|---|
| Kuopio University Hospital |
Finland,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Bisect Offset (BSO) | BSO is the ratio of medial to lateral displacement of the patella (Brossmann et al. Radiology 1993). | One year | No |
| Secondary | Lateral Patellar Displacement (LPD) | LPD is the lateral displacement of the patella. | One year | No |
| Secondary | Patellar Tilt Angle (PTA) | PTA measures the lateral tilting of the patella. | One year | No |
| Secondary | Sulcus Angle | Sulcus Angle measures the angle formed by the medial and lateral borders of the trochlea | One year | No |
| Secondary | Insall-Salvati-ratio | Insall-Salvati-ratio measures the ratio of the length of the patella to the length of the patellar ligament. | One year | No |