Peptic Ulcer [Iowa Type (107680.0010)] Clinical Trial
Official title:
Risk of Uncomplicated Peptic Ulcer in the General Population
The analyses are conducted in a previous population-based cohort study using The Health
Improvement Network database in the UK (Cai et al 2009).The aims of the post hoc analyses
are:
To estimate the relative risk of uncomplicated symptomatic peptic ulcer (UPU) associated
with use of low dose aspirin (ASA) and other anti-inflammatory drugs (NSAIDs, steroids) in
the general population To estimate the dose-response and duration-response associated with
use of these drugs To estimate the relative risk of UPU associated with naive/non-naive use
of low dose ASA in the general population To evaluate the effect of proton pump inhibitors
(PPI) (alone or in combination with anti-inflammatory drugs) on the occurrence of UPU in the
general population To investigate the management of low dose ASA/oral antiplatelets after
UPU
Risk of uncomplicated peptic ulcer in the general population ;
Observational Model: Cohort, Time Perspective: Retrospective