Open Angle Glaucoma With a Progressive Visual Field Clinical Trial
Official title:
Corneal Biomechanics and Continuous IOP Monitoring Using Soft Contact Lenses in Glaucomatous Patients
Ocular hypertension and its fluctuations is a major risk factor of glaucoma onset and
progression. In normal eyes, IOP presents a circadian rhythm, but in glaucomatous eyes IOP
circadian rhythm is altered and varied widely between patients. To date, the only way to
evaluate 24 hour IOP fluctuations is a regular GAT-IOP measurement during a 24-hour
hospitalization. This method is expensive and does not reflect physiological conditions
because it requires IOP measurements during sleeping periods that may potentially produce
artifacts.
Sensimed AG has developed a new medical device SENSIMED Triggerfish® that enables a 24-hour
continuous monitoring of IOP fluctuations. As any IOP measurements methods, this medical
device might be influenced by corneal properties of the cornea as central corneal thickness,
keratometry or biomechanics. We, therefore, investigate the corneal lens tolerance,
potential modifications of corneal parameters after a 24-hour wear of the lens, and its
influence on data collected during the whole period of analysis. Then we will also analyze
the influence of corneal parameters on continuous IOP fluctuations measured with the contact
sensor and finally the correlation between data collected and the rate of progression
(severity) of glaucoma evaluated with visual field test or optic nerve head damages.
n/a
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic