Manipulation of Dietary Protein and the Anabolic Response

Condition Relevance: Skeletal Muscle Health, Sarcopenia Clinical Trial

— PRO-ADAPT  

Official title:

The Manipulation of Dietary Protein Intake on the Anabolic Response in Healthy Young Men

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01820975
• Other study ID #: METC 12-3-067
• Status: Completed
• Phase: N/A
• First received: March 18, 2013
• Last updated: March 21, 2017
• Start date: April 2013
• Est. completion date: February 1, 2017

Study information

• Verified date: May 2015
• Source: Maastricht University Medical Center
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

In the present study, the effect of habitual dietary protein on the anabolic response will be investigated.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 28
• Est. completion date: February 1, 2017
• Est. primary completion date: March 2015
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 18 Years to 35 Years

Eligibility

Inclusion Criteria:

• Males

• Aged between 18-35 years

• Healthy, recreationally active

• BMI < 30 kg/m2

Exclusion Criteria:

• Smoking

• Allergies to milk proteins (whey or casein)

• Vegetarians

• Diagnosed GI tract diseases

• Female

• Arthritic conditions

• A history of neuromuscular problems

• Previous participation in amino acid tracer studies

• Individuals on any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications

Related Conditions & MeSH terms

• Condition Relevance: Skeletal Muscle Health, Sarcopenia
• Focus: Anabolic Response to Food Intake in Young Individuals
• Sarcopenia

Intervention

Dietary Supplement:
• High protein intake

Other:
• Placebo comparator
No protein intake

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Maastricht University Medical Center

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Muscle protein fractional synthetic rate following protein ingestion	The ability of the muscle to synthesise new proteins will be assessed over a 3 h period following protein ingestion and will be compared between groups. This only occurs on one occasion.	3 hours