Idiopathic Membranous Nephropathy Clinical Trial
Official title:
Mechanism Research of Traditional Chinese Medicine (the Comprehensive Treatment Regimen) in Treating Idiopathic Membranous Nephropathy by Genomewide Association Studies
The purpose of this study is to analysis the different genotype in the idiopathic membranous nephropathy patients which with different therapeutic outcomes after treated by the Comprehensive Treatment Regimen or immunosuppressive agents, and so as to looking for ideal markers to assess appropriate treatment approach and the long-term efficacy.
Status | Unknown status |
Enrollment | 80 |
Est. completion date | August 2013 |
Est. primary completion date | August 2013 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 70 Years |
Eligibility |
Inclusion Criteria: - Clinical diagnosis of idiopathic membranous nephropathy - Chronic Kidney Disease (CKD)=3 stage(Glomerular Filtration Rate (GFR)=30ml/min)and 24 hour urinary protein=3g - Voluntarily participated in the study and signed an informed consent Exclusion Criteria: - Combined life-threatening complications such as serious infection - Abnormal glucose metabolism - Patients with malignant tumors or malignancy , HIV infection and a history of mental illness , acute central nervous system disease , serious gastrointestinal diseases,etc - Pregnancy or breast-feeding women - Undergoing other clinical trials |
Country | Name | City | State |
---|---|---|---|
China | Shanghai University of Traditional Chinese Medicine | Shanghai | Shanghai |
Lead Sponsor | Collaborator |
---|---|
Shanghai University of Traditional Chinese Medicine |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Genome-wide single-nucleotide-polymorphism of IMN patients treated by the Comprehensive Treatment Regimen or conventional approach | Screening for single-nucleotide-polymorphism as the prognostic factor for the TCM intervention of IMN patients. | one year |
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