Pulmonary Aspiration of Gastric Contents Clinical Trial
Official title:
Gastric Residual Volume After He Intake Of Maltodextrin And Glutamine. A Randomized Double-Blind, Crossover Study
Carbohydrates (CHO)-based drinks 2h before the induction of anesthesia are recommended to decrease insulin resistance. The addition of glutamine (GLN) in these beverages may enhance the benefits of CHO alone. However, only a few studies tested the safety of this formula. The objective of this study was to evaluate the gastric residual volume (GRV) after the intake of a beverage containing CHO plus GLN using magnetic resonance (MRI).
Status | Completed |
Enrollment | 11 |
Est. completion date | July 2012 |
Est. primary completion date | June 2012 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Male |
Age group | 21 Years to 30 Years |
Eligibility |
Inclusion Criteria: - Young male volunteers (aged between 21 and 30 years-old) with body mass index (BMI) between 20 and 29 kg/m2 and without either acute or chronic illness in the last 3 months. Exclusion Criteria: - non-adherence to any phase of the study protocol, - gastroesophageal reflux disease, - previous history of intolerance to lactose, - gastroparesis or history of poor gastric emptying, - diabetes mellitus, and - previous abdominal surgery |
Allocation: Randomized, Endpoint Classification: Safety Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Prevention
Country | Name | City | State |
---|---|---|---|
Brazil | Hospital Santa Rosa | Cuiaba | Mato Grosso |
Lead Sponsor | Collaborator |
---|---|
Federal University of Mato Grosso do Sul |
Brazil,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Gastric residual volume (GVR) ("change" is being assessed) | We measured the GRV by MRI immediately after ingestion (T0)and the changes of GVR after 120 (T120)and 180 minutes (T180)- "change" is being assessed | immediately after ingestion (T0), 120 minutes after (T120) and 180 (T180) minutes after ingestion | Yes |
Secondary | Vomiting | We observed whether the volunteer presented vomiting during the experiment | 180 minutes | Yes |
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