Clinical Trials Logo

Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT01762618
Other study ID # EMOCUIDA/FPM-0211
Secondary ID
Status Completed
Phase N/A
First received December 18, 2012
Last updated July 8, 2014
Start date January 2012
Est. completion date July 2013

Study information

Verified date July 2014
Source Barcelonabeta Brain Research Center, Pasqual Maragall Foundation
Contact n/a
Is FDA regulated No
Health authority Spain: Comité Ético de Investigación Clínica
Study type Interventional

Clinical Trial Summary

A randomized controlled trial designed to test the effectiveness of a psychological intervention based on group therapy for the caregivers of Alzheimer's disease patients. The intervention consists of 14 sessions of a cognitive-behavioral psychological group therapy. This study aims to demonstrate that Alzheimer's patients' caregivers can benefit from group counseling, with an improvement in mood state, quality of life, perceived burden and a decrease in anxiety and depression. Two evaluations will be done: before the therapy sessions (basal) and when intervention is finished (final).


Description:

The aim of this study is to conduct group therapy with Alzheimer's caregivers at three centers in the province of Barcelona: Hospital El Carme Badalona, Sanitary Center of Les Corts and SarriĆ .

The therapy sessions are conducted by an expert in group therapy (from the sponsor Pasqual Maragall Foundation) and the social worker of each of the centers. The study takes place for four months and consists of weekly therapy sessions of an hour and a half each (14 sessions in total), based on cognitive and behavioral theory. The participants and the control group are evaluated at the beginning and at the end of the study in terms of mood, quality of life, anxiety and depression.

This study aims to demonstrate that Alzheimer's patient's caregivers can benefit from group counseling, resulting in an improvement in their emotional state, perceived burden, quality of life and a more positive attitude coping with the new situation.


Recruitment information / eligibility

Status Completed
Enrollment 83
Est. completion date July 2013
Est. primary completion date April 2013
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 18 Years to 95 Years
Eligibility Inclusion Criteria:

- To be the principal caregiver of a person with Alzheimer's disease

- The patient has a possible or probable diagnosis of Alzheimer's disease made for an Accredited Dementia Unit.

- The patient score in the Global Deterioration Scale must be: 4, 5 or 6A.

- The caregiver must dedicate at least 5 hours a day or spend a significant part of his time to care-related tasks

- The caregiver must sign the Informed Consent

Exclusion Criteria:

- To receive a financial compensation for the care of the patient

- The caregiver or the patient has a psychiatric illness according to the DSM-IV TR, such that the investigator considers it might hinder the dynamics of the group and affect the objectives of the study

- Be receiving some type of formal counseling (conducted by a therapist

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Supportive Care


Related Conditions & MeSH terms


Intervention

Behavioral:
Cognitive Behavioral Therapy Group
Therapy Groups

Locations

Country Name City State
Spain Hospital del Carme Badalona Barcelona
Spain Primary Assistant Center Les Corts Barcelona Catalonia
Spain Primary Assistant Center Sarrià Barcelona Catalonia

Sponsors (1)

Lead Sponsor Collaborator
Barcelonabeta Brain Research Center, Pasqual Maragall Foundation

Country where clinical trial is conducted

Spain, 

Outcome

Type Measure Description Time frame Safety issue
Other Change from baseline compared to the control and active arms using the SF-36 v2 (Short Form-36 Health Survey), a questionnaire that measures the Quality of Life related to Health. The SF-36 has 36 items that assesse eight health concepts: limitations in physical activities because of health problems; limitations in social activities because of physical or emotional problems; limitations in usual role activities because of physical health problems); bodily pain; general mental health (psychological distress and well-being); limitations in usual role activities because of emotional problems; vitality (energy and fatigue); and general health perceptions. This version of the instrument asks for participants to reply to questions according to how they have felt over the previous four weeks. The items use Likert-type scales, some with 3, 5 or 6 points. Pre-treatment and 4 weeks post treatment No
Other Change from baseline compared to the control and active arms using the Hospital Anxiety and Depression Scale (HADS) The HADS is a fourteen item scale with a Likert response from 0 to 3 that generates ordinal data. Seven of the items relate to anxiety and seven relate to depression. Pre-treatment and 4 weeks post treatment No
Primary Change from baseline in POMS Scale ("Profile of Mood States") Change from baseline compared to the control and active arms using the Profile of Mood State (POMS) validated in structure and content for the Spanish language. This scale is a popular instrument for mood evaluation. It comprises 44 items (with a Likert response from 0 to 4), representing six conceptual dimensions: tension, depression,anger, vigour, fatigue and friendliness. Pre-treatment and 4 weeks post treatment No
Secondary Change from baseline compared to the control and active arms using the Martin and cols. scale to assess the overload level of the family caregivers of patients with probable or possible Alzheimer's disease or other advanced stage dementia. Martin and cols. scale is an adaptation of the Zarit questionnaire to assess the overload level of the caregiver. It is a self administered questionnaire, with 22 items with each item scored from 1 ('none') to 5 (`nearly always'). Pre-treatment and 4 weeks post treatment No