Stress Hormones, Mood and Women's Sexual Desire (MODEST) — MODEST

Hypoactive Sexual Desire Disorder (HSDD) Clinical Trial

Official title:
Stress Hormones, Mood and Women's Sexual Desire (MODEST)

Status Completed

Clinical Trial Summary

Women with Hypoactive sexual desire disorder (HSDD) have all measures of testosterone activity comparable to controls but lower levels of dehydroepiandrosterone (DHEA). Although DHEA is a precursor of testosterone it has other actions including involvement in the stress system. It is also linked to mood. This study focuses on measures of childhood stress, current mood and salivary stress hormones, in women with and without HSDD. We hypothesize that low levels of DHEA reflect dysfunction of the neuroendocrine stress response system involving the brain, pituitary and adrenal glands where DHEA is produced.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Hypoactive Sexual Desire Disorder (HSDD)
Hypokinesia
Sexual Dysfunctions, Psychological

Clinical Trial Details

NCT number	NCT01702818
Study type	Observational
Source	University of British Columbia
Contact
Status	Completed
Phase
Start date	February 2012
Completion date	November 2016

View Details

See also
Status	Clinical Trial	Phase
Withdrawn	`NCT03619005` - Prasterone (DHEA) for the Treatment of Hypoactive Sexual Desire Disorder (HSDD) - Second Study	Phase 3
Completed	`NCT03080298` - Study of the Efficacy and Safety of BP101 in Female Patients With Decrease or Loss of Sexual Desire	Phase 2
Completed	`NCT00349791` - Study to Assess the Efficacy/Safety of Transdermal Testosterone Patches in Naturally Menopausal Women With Low Libido	Phase 3
Completed	`NCT02070029` - Acupuncture for Sexual Dysfunction	N/A