Dry Age Related Macular Degeneration Clinical Trial
Official title:
A Phase I/IIa, Open-Label, Single-Center, Prospective Study to Determine the Safety and Tolerability of Sub-retinal Transplantation of Human Embryonic Stem Cell Derived Retinal Pigmented Epithelial (MA09-hRPE) Cells in Patients With Advanced Dry Age-related Macular Degeneration(AMD)
To evaluate the safety and tolerability of MA09-hRPE cellular therapy in patients with advanced dry AMD To evaluate the safety of the surgical procedures when used to implant MA09-hRPE cells To assess the number of hRPE cells to be transplanted in future studies To evaluate on an exploratory basis potential efficacy endpoints to be used in future studies of MA09-hRPE cellular therapy.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT00751361 -
Dry Age-Related Macular Degeneration (AMD) Treatment With Rheopheresis Trial
|
Phase 4 | |
| Enrolling by invitation |
NCT03305029 -
The Safety and Tolerability of Sub-retinal Transplantation of SCNT-hES-RPE Cells in Patients With Advanced Dry AMD
|
Phase 1 | |
| Completed |
NCT01344993 -
Safety and Tolerability of Sub-retinal Transplantation of hESC Derived RPE (MA09-hRPE) Cells in Patients With Advanced Dry Age Related Macular Degeneration
|
Phase 1/Phase 2 | |
| Completed |
NCT00804102 -
Transcorneal Electrical Stimulation Therapy for Retinal Disease
|
N/A | |
| Suspended |
NCT00541333 -
Weekly Vaccination With Copaxone as a Potential Therapy for Dry Age-related Macular Degeneration
|
Phase 1 | |
| Completed |
NCT00429936 -
Study of Fenretinide in the Treatment of Geographic Atrophy Associated With Dry Age-Related Macular Degeneration
|
Phase 2 |