Glycemia During Coronary Artery Bypass Graft Clinical Trial
Official title:
The Effect of Clonidine in Glycemia During Coronary Artery Bypass Graft With Cardiopulmonary By-pass.
The purpose of this study is the randomized blind research of the assessment of the different levels of glycemia during Coronary Artery Bypass Graft (CABG) with cardiopulmonary by-pass (CPB) between clonidine and placebo. As clonidine decrease the inflammatory response during cardiac surgery, the investigators would like to know if the glycemia levels in clondine group will be lower than placebo group.
| Status | Completed |
| Enrollment | 46 |
| Est. completion date | May 2012 |
| Est. primary completion date | January 2012 |
| Accepts healthy volunteers | No |
| Gender | Both |
| Age group | 45 Years to 80 Years |
| Eligibility |
Inclusion Criteria: - elective CABG EF > 40% Sinus ritmy Exclusion Criteria: - precordialgia emergency surgery combinated surgery not agreement |
Allocation: Randomized, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Investigator), Primary Purpose: Treatment
| Country | Name | City | State |
|---|---|---|---|
| Brazil | National institut of Cardiology | Rio de Janeiro | RJ |
| Lead Sponsor | Collaborator |
|---|---|
| Federal University of Juiz de Fora |
Brazil,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | sedation | Clonidine 2 mg/kg IV. assessment sedation with Ransay scale | 2 years | Yes |
| Secondary | Glycemia | clonide 2 mg/kg. assessment the glycemia during CPB. | 2 years | Yes |